Results 121 to 130 of about 420,339 (355)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Randomized Controlled Trial Comparing Interscalene Nerve Block versus Continuous Infusion Local Anesthetic Pump for Outpatient Arthroscopic Rotator Cuff Repair (SS‐34) [PDF]

, 2006
Darby Webb, Dan Guttmann, John B. Reid, Patrick W. Cawley, James H. Lubowitz   +4 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Applications of aerospace technology in biology and medicine [PDF]

Utilization of National Aeronautics and Space Administration (NASA) technology in medicine is discussed. The objective is best obtained by stimulation of the introduction of new or improved commercially available medical products incorporating aerospace ...
Bass, B., Beall, H. C., Brown, J. N., Jr., Clingman, W. H., Eakes, R. E., Kizakevich, P. N., Mccartney, M., Rouse, D. J.   +7 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling

Experimental Physiology
Endotoxin administration is commonly used to study the inflammatory response, and though traditionally given as a bolus injection, it can be administered as a continuous infusion over multiple hours.
Kristen A. Windoloski, Susanne Janum, Ronan M. G. Berg, Mette S. Olufsen   +3 more
doaj   +1 more source

Effect of acepromazine or dexmedetomidine associated with methadone on anesthetic induction with propofol at a rate of 1 mg/kg/min in healthy dogs: A randomized clinical trial

Open Veterinary Journal
Background: Presedation before general anesthesia helps reduce patient anxiety and facilitates anesthetic induction. Acepromazine and dexmedetomidine are widely used in dogs; however, these drugs cause cardiopulmonary alterations that may have a ...
Gabriela Pereira Souza, Lucas Wamser Fonseca Gonzaga, Pablo Henrique Silva Avelar, Jelieny Aparecida Claudino, Marilda Onghero Taffarel, Marcos Ferrante   +5 more
doaj   +1 more source

Effects of propofol in lipid-based emulsion and in microemulsion on the incidence of endothelial lesion in rabbits [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME).
Cristian Durço Paço, Matheus Fachini Vane, Rafael Bicarato de Andrade, Maria Aparecida Domingues, Lidia Raquel de Carvalho, Daniela Carvalho dos Santos, Regina Kiomi Takahira, Norma Sueli Pinheiro Modolo, Luiz Antonio Vane   +8 more
doaj  

Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children.

PLoS ONE, 2019
We investigated the hemodynamic and mortality effects of continuous ketamine infusion in critically ill pediatric patients. We conducted a retrospective cohort study in a tertiary pediatric intensive care unit (PICU).
Sojin Park, Ah Young Choi, Esther Park, Hyo Jung Park, Jaehyun Lee, Hukyoung Lee, JeongMee Kim, Joongbum Cho   +7 more
doaj   +1 more source

Clinical Dopplerographic Correlates of a Continuous Long-Term Ethylmethylhydroxypyridine Succinate Infusion in Acute Concomitant Traumatic Brain Injury [PDF]

, 2016
Е. А. Абрамова, A.O. Trofimov, G. А. Boyarinov, О.В. Военнов   +3 more
openalex   +1 more source