Results 81 to 90 of about 2,182,247 (328)

Is Consciousness Computable? Quantifying Integrated Information Using Algorithmic Information Theory [PDF]

, 2014
In this article we review Tononi's (2008) theory of consciousness as integrated information. We argue that previous formalizations of integrated information (e.g. Griffith, 2014) depend on information loss.
Griffith, Virgil, Maguire, Phil, Maguire, Rebecca, Moser, Philippe   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Test Pyramid 2.0: AI-assisted testing across the pyramid

Frontiers in Artificial Intelligence
Ensuring robust test coverage, high code quality, and a strong security posture are persistent challenges in modern industrial software development, especially as systems grow in complexity and release cycles accelerate with recent Artificial ...
Priyank Desai, Snahil Singh, Shubham Amilkanthwar   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Integrated Visual Software Analytics on the GitHub Platform

Computers
Readily available software analysis and analytics tools are often operated within external services, where the measured software analysis data are kept internally and no external access to the data is available. We propose an approach to integrate visual
Willy Scheibel, Jasper Blum, Franziska Lauterbach, Daniel Atzberger, Jürgen Döllner   +4 more
doaj   +1 more source

Stochastic integration for uncoupled continuous-time random walks [PDF]

Continuous-time random walks are pure-jump processes with several applications in physics, but also in insurance, finance and economics. Based on heuristic considerations, a definition is given for the stochastic integral driven by continuous-time random
Germano, Guido, Politi, Mauro, Scalas, Enrico, Schilling, René L.   +3 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Revisioning Healthcare Interoperability System for ABI Architectures: Introspection and Improvements

Information
The integration of systems for Adaptive Business Intelligence (ABI) in the healthcare industry has the potential to revolutionize and reform the way organizations approach data analysis and decision-making.
João Guedes, Júlio Duarte, Tiago Guimarães, Manuel Filipe Santos   +3 more
doaj   +1 more source

Heat Integration of a Continuous Reforming Process

Chemical Engineering Transactions, 2011
preview not available - see full-text PDF article.
C. Liang, X. Feng
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source