Results 151 to 160 of about 3,401,628 (310)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2014 Mapsiennes, Mapsiens, Depuis Mars 2014 un vaste chantier de mise en commun et d'édition de toutes les fiches et modèles ayant été produit dans le cadre de MAPS est en cours.
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, 2020 A vos agendas ! Voici les dates à retenir pour MAPS 13 Lancement de l'appel à candidature : 22 janvier 2020 Date limite de dépôt des candidatures : 22 février 2020 repoussée au 15 mars via le formulaire en ligne, voir sur cette page Notification d ...
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
, 2013 La première formation MAPS 1 a eu lieu en 2009 à Oléron FORMATEURS Arnaud Banos Frédéric Amblard Nicolas Bécu Eric Daudé Nicolas Marilleau David Sheeren INTERVENANTS Johnny Douvinet Michel Etienne Patrice Langlois Franck Varenne PARTICIPANTS Behar ...
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Spatially Continuous Maps of Disease Risk: An Analysis of Mortality Disparities in the United States. [PDF]
AJPM FocusRuiz-Suarez S, Brown P.
europepmc +1 more source
, 2014 MAPS 7 approche! Rappel pour la guest list! Lieu : Club Belambra "Les tuquets" à Seignosse, dans les Landes, Date : du dimanche 29 juin au soir 19h30 au vendredi 4 juillet midi, Pour le contenu scientifique: Nous travaillerons sur des modèles qu'il ...
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