Results 171 to 180 of about 3,401,628 (310)

MAPS 11 sur les risques, c'est parti!

open access: yes, 2017
  La session 11 de MAPS aura lieu du 10 au 15 juin, au centre CAES du CNRS de la Villa Clythia à Fréjus.  La liste des invités sera prochainement arrêtée.
Réseau MAPS
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Preserved topography, lateralization, selectivity, and functional connectivity of the language network in older brains. [PDF]

open access: yesNat Commun
Billot A   +8 more
europepmc   +1 more source

Modalités de participation MAPS 8

open access: yes, 2015
Modalités de participation La participation à MAPS 8 est soumise à sélection (étudiée par le comité scientifique). Les tarifs sont fixés en fonction des statuts (voir ci-dessous).
Réseau MAPS
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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