Results 51 to 60 of about 70,213 (257)

The Current Status of Autotitrating Continuous Positive Airway Pressure Systems in the Management of Obstructive Sleep Apnea

Canadian Respiratory Journal, 2005
BACKGROUND: Autotitrating continuous positive airway pressure (APAP) devices have the potential to address some of the disadvantages of titration and treatment with conventional continuous positive airway pressure (CPAP).
David Hailey, Philip Jacobs, Irvin Mayers, Shaila Mensinkai   +3 more
doaj   +1 more source

Regional gas exchange evaluation during ex vivo lung perfusion in a swine model of localized lung dysfunction

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Ex vivo lung perfusion (EVLP) allows the evaluation of lungs that do not meet standard transplantation criteria. Current procedures do not permit the identification of regional functional deficits. We investigated the feasibility of assessing lobar gas exchange during EVLP in a swine model.
Giulia Maria Ruggeri, Elena Chiodaroli, Matteo Montoli, Sara Pieropan, Alessandro Santini, Gianluca Lopez, Michele Battistin, Luigi Vivona, Sebastiano Maria Colombo, Jacopo Fumagalli, Eleonora Carlesso, Stefano Ferrero, Lorenzo Rosso, Stefano Gatti, Antonio Maria Pesenti, Giacomo Grasselli, Alberto Zanella   +16 more
wiley   +1 more source

Analysis of energy expenditure and behavioral characteristics in different mouse strains under normal and disease conditions

Animal Models and Experimental Medicine, EarlyView.
Mouse metabolic and behavioral phenotypes are tightly linked to strain, age and disease state, with distinct dysregulation in each disease model, underscoring the need for standardized preclinical experimental conditions. Abstract Background Metabolic and behavioral traits in mice exhibit substantial variability across strains, ages, and disease states,
Jiacheng Zeng, Yuanjun Ji, Yan Zou, Jing Tan, Teng Wu, Conghui Shen, Tongsheng Huang, Shijie Xiong, Mengying Liu, Maoquan Yang, Jingwei Lai, Jiangwei Ma, Junhong Wan, Xinlu Fu, Jiang Qian, Hui Li, Ludong Yuan, Weibin Cai   +17 more
wiley   +1 more source

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

The Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy, Alice Nishigaki, Matthew C. Gage, Renato L. Previdelli   +3 more
wiley   +1 more source

The Effect of Continuous Positive Airway Pressure on Middle Ear Pressure

Southeastern European Medical Journal
Aim of the study: The study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure. Methods: Forty-two patients with obstructive sleep apnea (OSA) were assigned to the study group. The patients underwent standard
Mirjana Grebenar Čerkez, Željko Zubčić, Stjepan Jurić, Jelena Šarić Jurić, Jelena Kovačević, Darko Dukić, Darija Birtić   +6 more
doaj   +1 more source

Continuous positive airway pressure.

Canadian family physician Medecin de famille canadien, 2019
Continuous positive airway pressure (CPAP) therapy provides a pneumatic splinting of the upper airways in obstructive sleep apnea (OSA). In spite of several CPAP therapy benefits, adherence remains a major problem than physician should monitor carrefully verify. Common interface-related side effects may contribute to therapy failure.
Peter Ran, Yang, Christina, Korownyk
openaire   +4 more sources

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Altitude-Associated Central Apnea in Continuous Positive Airway Pressure Therapy

Sleep Science
Introduction At high altitudes, hypobaric hypoxia leads to central apneas in both healthy adults and patients with obstructive sleep apnea. This condition correlates with intermittent desaturation and disruption of sleep.
Gustavo Adolfo Gaitan Quintero, Leidy Paola Prada Romero, Ana María González, María Angélica Bazurto-Zapata   +3 more
doaj   +1 more source

Devoted or negotiated routes of adherence: Narratives of patients with obstructive sleep apnoea using a continuous positive airway pressure device

Nursing Open, 2019
Aims To explore the narratives of patients about receiving a diagnosis of obstructive sleep apnoea and using a continuous positive airway pressure device. Design A qualitative design with a narrative approach.
Margareta Møkleby, Anne Marit Mengshoel
doaj   +1 more source