Results 61 to 70 of about 8,956,014 (290)

The Rationale Behind a Continuous Nasal Positive Airway Pressure Machine That Approximates the Nasal Cycle During Sleep

, 2017
Normal nasal airflow alternates in dominance between the two nostrils with an ultradian rhythm called the “nasal cycle.” The nasal cycle is thought to enable the patent airway to perform the majority of the air-conditioning functions, while the congested
White, D, Bartley, J
core   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Effect of continuous positive airway pressure on day/night rhythm of prothrombotic markers in obstructive sleep apnea [PDF]

, 2013
Obstructive sleep apnea (OSA) has been associated with an increased risk of atherothrombotic events. A prothrombotic state might partially explain this link.
Mills, Paul J., Gamst, Anthony C., Natarajan, Loki, Loredo, José S., Wolfson, Tanya, Ancoli-Israel, Sonia, von Känel, Roland, Dimsdale, Joel E.   +7 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Treatment of obstructive sleep-disordered breathing with positive airway pressure systems

European Respiratory Review, 2007
Positive airway pressure systems are widely used to treat patients with moderate-to-severe obstructive sleep-disordered breathing. The application of stable continuous positive airway pressure (CPAP) via the nose (nasal CPAP) has been the mainstay of ...
D. Pevernagie, J. F. Masa, J. C. Meurice, R. Farré, O. Marrone, D. Rodenstein   +5 more
doaj  

Development of a guide for continuous positive airway pressure use - A good fit: Making continuous positive airway pressure work for you

Canadian Journal of Respiratory Therapy
# Background Obstructive sleep apnea (OSA) is highly prevalent in veterans with mental illnesses such as post-traumatic stress disorder (PTSD). Untreated OSA reduces the effectiveness of the treatment of PTSD.
Adeel Meraj, Lauren Koep, Muhammad R. Baig   +2 more
doaj   +1 more source

Comparison of the effects of continuous positive airway pressure, oral appliance and exercise training in obstructive sleep apnea syndrome

Clinics, 2013
OBJECTIVE: There are several treatments for obstructive sleep apnea syndrome, such as weight loss, use of an oral appliance and continuous positive airway pressure, that can be used to reduce the signs and symptoms of obstructive sleep apnea syndrome ...
Teresa Cristina Barros Schutz, Thays Crosara Abrahao Cunha, Thais Moura-Guimaraes, Gabriela Pontes Luz, Carolina Ackel-D'Elia, Eduardo da Silva Alves, Gilberto Pantiga Junior, Marco Tulio de Mello, Sergio Tufik, Lia Bittencourt   +9 more
doaj   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

Advanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi, Antonio Ferraro, Francesco Coccimiglio, Tiziana Ritacco, Alberto Astolfo, Michele Giocondo, Vincenzo Formoso, Raffaele Giuseppe Agostino, Francesco Iacoviello, Ioannis Papakonstantinou, Alessandro Olivo   +10 more
wiley   +1 more source

Thermally Drawn Bioelectric Catheters: Enabling Proprioceptive Endovascular Navigation

Advanced Intelligent Systems, EarlyView.
This work introduces a novel bioelectric navigation system eliminates the need for harmful fluoroscopy during endovascular surgeries. A bespoke 16‐electrode catheter is fabricated using rapid thermal drawing and laser micro‐machining. Paired with a real‐time tracking algorithm fusing vascular geometry detection and distance estimation, this technology ...
Alex Ranne, Heiko Maier, Jinshi Zhao, Songli Moey, Ayhan Aktas, Manik Chana, Burak Temelkuran, Nassir Navab, Ferdinando Rodriguez y Baena   +8 more
wiley   +1 more source

Out-of-hospital noninvasive ventilation: epidemiology, technology and equipment

Pediatric Reports, 2012
Noninvasive ventilation has been utilized successfully in the pre- and out-of-hospital settings for a variety of disorders, including respiratory distress syndrome in neonates, neurologic and pulmonary diseases in infants and children, and heart failure ...
John Scott Baird, Thyyar M. Ravindranath
doaj   +1 more source