Results 81 to 90 of about 4,751,282 (207)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Data Workflow - A Workflow Model for Continuous Data Processing [PDF]
, 2010 Online data or streaming data are getting more and more important for enterprise information systems, e.g. by integrating sensor data and workflows. The continuous flow of data provided e.g.
Wombacher, Andreas
core +1 more source
CHIMIAElectrochemistry is significantly contributing to the technological revolution of organic synthesis, where the implementation of different techniques has garnered innovative and scalable synthetic methodologies.
Gabriele Laudadio
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
From the Editor-in-Chief: Stem-to-Stern, Continuous Process for Biologics?
Call me jaded. One of the latest fads in the production of biologics is “continuous processing.” So let’s concede that the upstream realm can lend itself to continuous processing, but the really hard stuff was always on the downstream side.
Keith L. Carson
core +1 more source
, 2021 Carbon dioxide (CO2) laser is widely used in commercial and industrial fields to process various materials including polymers, most of which have high absorptivity in infrared spectrum.
Mitsutaka Fukuda +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Biologics: Targets & TherapyRanjit Ranbhor Pergament & Cepeda LLC, Florham Park, NJ, 07932, USACorrespondence: Ranjit Ranbhor, Pergament & Cepeda LLC, Florham Park, NJ, 07932, USA, Tel +1 973 967 0490, Email ranjitranbhor@gmail.comPurpose: This review examines recent advances in ...
Ranbhor R
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Accidental Continuous Releases from Coal Processing in Semi-Confined Environment
Energies, 2013 Notwithstanding the enforcement of ATEX EU Directives (94/9/EC of 23 March 1994) and safety management system application, explosions in the coal sector still claim lives and cause huge economic losses.
Bruno Fabiano +2 more
doaj +1 more source