Results 31 to 40 of about 8,930 (266)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Acta Scientiarum: Animal Sciences, 2012 The experiment was conducted to evaluate Brachiaria decumbens cv. Basilisk at different sites of the same pasture featuring varying grazing intensities (under grazed, properly grazed and overgrazed).
Manoel Eduardo Rozalino Santos +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
GrassesSward height is a practical indicator for defining management targets that reflect pasture structure. The complexity of integrated systems, including the coexistence of trees, crops, and livestock, can modify animal grazing distribution and microhabitat ...
Renata Franciéli Moraes +7 more
doaj +1 more source
A jumping index of jumping stocks? An MCMC analysis of continuous-time models for individual stocks
Journal of Empirical Finance, 2009 This paper examines continuous-time models for the S&P 100 index and its constituents. We find that the jump process of the typical stock looks significantly different than that of the index. Most importantly, the average size of a jump in the returns of the typical stock is positive, while it is negative for the index.
Pollastri, Alessandro +3 more
openaire +3 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Revista Brasileira de Zootecnia, 2007 O experimento foi conduzido com o objetivo de avaliar a influência de duas intensidades (moderada e baixa) e de dois métodos de pastejo (lotação contínua e rotacionada) no fluxo de biomassa aérea de azevém, medido por meio dos fluxos de crescimento ...
Guilherme Fernandes Cauduro +6 more
doaj +1 more source
Continuous-time restless bandit and dynamic scheduling for make-to-stock production [PDF]
IEEE Transactions on Robotics and Automation, 2003 We study the "Whittle relaxation" version of the continuous time, discrete, and continuous state space Restless Bandit problem under the discounted cost criterion. Explicit expressions of Whittle's priority indexes, which generalize the Gittins indexes, are derived.
Hongler, M.-O., Dusonchet, F.
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source