Results 91 to 100 of about 35,220 (306)

A comparison of the hypoglycemic effect of insulin with systemic venous and portal venous administration [PDF]

open access: yes, 1963
The hyperglycemic effect of insulin by prolonged intraportal and systemic infusion was measured in unanesthetized dogs with a modified portacaval transposition. There was no significant difference in response with the two routes of administration.
Bell   +55 more
core   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

Coming of age: the artificial pancreas for type 1 diabetes. [PDF]

open access: yes, 2016
The artificial pancreas (closed-loop system) addresses the unmet clinical need for improved glucose control whilst reducing the burden of diabetes self-care in type 1 diabetes.
Hovorka, Roman, Thabit, Hood
core   +2 more sources

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

Clinical Efficacy of Two Different Methods to Initiate Sensor-Augmented Insulin Pumps: A Randomized Controlled Trial

open access: yesJournal of Diabetes Research, 2016
Aim. To analyze clinical effect of a novel approach to initiate sensor-augmented insulin pumps in type 1 diabetes mellitus (T1DM) patients through early real-time continuous glucose monitoring (RT-CGM) initiation. Methods. A 26-week pilot study with T1DM
Jesus Moreno-Fernandez   +3 more
doaj   +1 more source

Diabetes Mellitus tipo 1 e bomba infusora de insulina em idade pediátrica [PDF]

open access: yes, 2012
Trabalho complementar (Monografia) realizado no âmbito da Unidade Curricular Estágio da Licenciatura em Ciências da Nutrição da Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto, sob orientação de Dra.
Ungureanu, Mara Cristina
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Effect of insulin infusion line on glycaemic variability in a perioperative high dependency unit (HDU): a prospective randomised controlled trial

open access: yesAnnals of Intensive Care, 2017
Background Glucose control is an important issue in post-operative patients. The objective here was to compare two insulin infusion lines by syringe pumps to assess the impact of medical devices on glycaemic variability in surgical patients under ...
Stéphanie Genay   +9 more
doaj   +1 more source

The State Of The Science Of Continuous Subcutaneous Insulin Infusion Use By Adolescents and Adults With Type 1 Diabetes [PDF]

open access: yes, 2013
Background and Significance: Diabetes mellitus is a collection of metabolic diseases, characterized by high blood sugar level, but stemming from different causes (ADA, 2005).
Cooper, Bomie
core   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

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