Results 101 to 110 of about 35,220 (306)

Insulin mediated upregulation of the renin angiotensin system in human subcutaneous adipocytes is reduced by Rosiglitazone [PDF]

, 2005
Background: Obesity associated hypertension is likely to be due to multiple mechanisms. Identification of the renin-angiotensin system (RAS) within adipose tissue does, however, suggest a potential causal role for it in obesity-associated hypertension ...
Chetty, Rajkumar, Coppack, Simon, Harte, A. L. (Alison L.), Katz, Jonathan, Kumar, Sudhesh, McTernan, P. G. (Philip G.), Smith, Stephen   +6 more
core   +1 more source

On the Molecular Diffusion Dynamics Between Subcutaneous Tissue and Microneedles for Wearable Continuous Glucose Monitoring

Advanced NanoBiomed Research, EarlyView.
In this study, we investigate the dynamics of glucose diffusion between subcutaneous tissue and hydrogel‐filled microneedles. Specifically, we examine how hydrogel thickness, microneedle size, and glucose concentration influence diffusion. This study provides an experimental reference to the wearable biosensor community researching microneedle‐based ...
Wensheng Lin, Binbin Cui, Xuecheng He, Suo Tu, Shilei Dai, Xinran Zhang, Ivo Pang, Xiaonan Chen, Jixiang Zhu, Shiming Zhang   +9 more
wiley   +1 more source

The education of patients in prandial insulin dosing related to the structure of bolus calculators [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2010
The metabolic effect of insulin pump therapy depends on precise adjustments of insulin to food intake ratio. Calculation of prandial insulin dose is a complex process employing many variant factors such as pre-prandial glucose and carbohydrate (CHO ...
Marlena Błazik, Ewa Pańkowska
doaj  

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Conventional insulin pump therapy in two neonatal diabetes patients harboring the homozygous PTF1A enhancer mutation: Need for a novel approach for the management of neonatal diabetes

The Turkish Journal of Pediatrics, 2017
The enhancer of PTF1A mutation causes developmental defects of the pancreas. This condition can result in insulin-requiring diabetes and exocrine pancreatic insufficiency.
Erdal Kurnaz, Zehra Aycan, Nurdan Yıldırım, Semra Çetinkaya   +3 more
doaj   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

Animal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao, Yuan Tian, Dan Li, Lei Tian, Hang Yu, Ziling Liu, Xin Gao, Yanqiong Wen, Fachun Wan, Zuo Wang, Weijun Shen, Xinwei Li, Lei Liu   +12 more
wiley   +1 more source

A nonparametric approach for model individualization in an artificial pancreas [PDF]

, 2015
The identification of patient-tailored linear time invariant glucose-insulin models is investigated for type 1 diabetic patients, that are characterized by a substantial inter-subject variability.
Cobelli, Claudio, De Nicolao, G., DEL FAVERO, Simone, Magni, L., Messori, M., Toffanin, C.   +5 more
core   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Continuous Subcutaneous Insulin Infusion in Italy: Third National Survey

Diabetes Technology & Therapeutics, 2015
Continuous subcutaneous insulin infusion (CSII) is increasing worldwide, mostly because of improved technology. The aim of this study was to evaluate the current status of CSII in Italy.Physicians from 272 diabetes centers received a questionnaire investigating clinical features, pump technology, and management of patients on CSII.Two hundred seventeen
Bruttomesso, Daniela, Laviola, Luigi, Lepore, Giuseppe, Bonfanti, Riccardo, Bozzetto, Lutgarda, Corsi, Andrea, Di Blasi, Vincenzo, Girelli, Angela, Grassi, Giorgio, Iafusco, Dario, Rabbone, Ivana, Schiaffini, Riccardo, V Montani, P Colleluori, V Paciotti, P Alfidi, J Grosso, S Tumini, P Cipriano, E Vitacolonna, G Di Vieste, A Minnucci, D Antenucci, G La Penna, M Taraborrelli, B Macerala, G Citro, G De Morelli, A Gnasso, C Irace, F Citriniti, N Lazzaro, M Bruzzese, F Mammì, F De Berardinis, E Santoro, G Corigliano, M Corigliano, M Parillo, M Schettino, V Di Blasi, R Fresa, G Annuzzi, L Bozzetto, V Bassi, C Santinelli, P Buono, E Mozzillo, V Russo, E De Feo, K Esposito, M Petrizzo, A Foglia, A Gatti, S Gentile, G Guarino, D Iafusco, A Zanfardino, C Lambiase, A Vitale, S Zucchini, G Maltoni, G Forlani, S Moscatiello, T Suprani, M Bensa, F Tomasi, M Monesi, M Nizzoli, S Acquati, G Chierici, B Milli, L Iughetti, B Predieri, R Cavani, S Romano, V Manicardi, M Michelini, M C Cimicchi, D Ugolotti, I Zavaroni, A Dei Cas, M Papi, E Dall'Aglio, L d'Amato, S M Tardio, M C Calderini, S Riboni, D Zavaroni, L Gastaldi, A Cirillo, V Graziani, P Di Bartolo, F Pellicano, C Di Seclì, S Amarri, A Lasagni, A Marsciani, A Pedini, U Pagliani, C Rossi, C Tortul, B Brunato, R Assaloni, G Zanette, P Livolsi, A Petrucco, K Tercelj, E Manca, R Candido, E Tommasi, G Tornese, E Faleschini, L Tonutti, S Agus, M Zanatta, A Rosolen, A R Maurizi, A Comici, F M Graziano, I Misischi, P Pozzilli, P Falasca, F Tuccinardi, G P Ricciardi, P Di Masa, M Ragonese, L Cipolloni, R Buzzetti, C Moretti, G Leto, A Crinò, S Bocchini, P Di Perna, M Giuliano, S Frontoni, I Malandrucco, D Pitocco, C Ventura, R Scalpone, F Toscanella, R Schiaffini, M Cappa, V Bonato, M De Bernardinis, M G Cavallo, F Leonetti, S Morano, E Mandosi, E Cicconetti, G Ciampittiello, M A Marini, D Sabato, A Napoli, F Giraudo, V Toscano, D Fava, F Massimiani, P Gargiulo, N Mecca, C Tubili, M R Nardone, L Morviducci, A Corsi, M L Manca-Bitti, S Arcano, S Leotta, C Suraci, F Chiaramonte, N Visalli, S Spirito, E Forte, C Palmacci, C Arnaldi, D Tosini, P Ponzani, M Patrone, R Guido, A Aglialoro, G Ghisoni, F Fabbri, C Bordone, D Maggi, R Cordera, N Minuto, E Rotondo, D Speranza, M Siri, S Carro, A Zappa, S Parmigiani, S Nieri, L Briatore, G Calvo, F Querci, G Lepore, R Trevisan, A Girelli, S Bonfadini, V Fuso, A Rocca, L Sciangula, E Orsi, A Laurenzi, R Bonfanti, G Frontino, C Berra, G Favacchio, L Bucciarelli, A C Bossi, I Mangone, C Giorda, F Cadario, S Savastio, P Barbieri, F Giorgino, O Lamacchia, S De Cosmo, M Delvecchio, M Baroni, M Songini, F Cardella, A Tumminia, G Salzano, C Lamanna, E Mannucci, S Rauch, R Franceschi, E Cipponeri, M Vedovato, A Galderisi, M Strazzabosco   +231 more
openaire   +8 more sources