Results 121 to 130 of about 35,220 (306)
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Inhaled insulin: overview of a novel route of insulin administration
Vascular Health and Risk Management, 2010 Lucy D MastrandreaDepartment of Pediatrics, School of Medicine and Biochemical Sciences, University at Buffalo, Buffalo, NY, USAAbstract: Diabetes is a chronic disease characterized by inadequate insulin secretion with resulting hyperglycemia.
Lucy D Mastrandrea
doaj
Frontiers in EndocrinologyBackgroundInsulin allergy, although rare in type 1 diabetes (T1DM), poses a significant clinical challenge due to the indispensable role of insulin therapy.
Yuwen Chen +3 more
doaj +1 more source
Phytotherapy Research, EarlyView.Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi +12 more
wiley +1 more source
A Mini‐Patch Magnetic Insulin Pump for Enhanced Delivery Resolution and Accuracy
Advanced Intelligent SystemsInsulin pumps typically use piston‐based mechanisms with bulky transmission components to convert rotary motion into the piston's forward motion. These mechanical transmission systems and insulin reservoirs occupy more than one‐third of pumps’ volume ...
Qiji Ze +5 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen +6 more
wiley +1 more source
Clinical and Experimental Obstetrics & GynecologyObjective: This study aims to compare the efficacy of two insulin administration methods — continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) — in managing glycemic levels and influencing pregnancy ...
Xiling Shi +4 more
doaj +1 more source
The insulin pump therapy in type 1 Diabetes: The importance of glucose variability [PDF]
Medicinski Podmladak, 2019 Introduction: The continuous subcutaneous insulin infusion regimen proved its effectiveness over multiple daily insulin doses. Although HbA1c has been brought to an optimal range, glucose variability remains one of the main challenges of this method. Aim:
Jozić Jovan +2 more
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Simplified Evaluation and Documentation of Data from Glucose Controlled Insulin Systems (GCIIS) [PDF]
, 1984 Göhl, M. +4 more
core +1 more source
Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery
Small, EarlyView.This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk +9 more
wiley +1 more source