Results 51 to 60 of about 35,220 (306)

When intensive insulin therapy (MDi) fails in patients with type 2 diabetes: Switching to GLP-1 receptor agonist versus insulin pump [PDF]

, 2016
Treatment with insulin, alone or with oral or injectable hypoglycemic agents, is becoming increasingly common in patients with type 2 diabetes. However, approximately 40% of patients fail to reach their glycemic targets with the initially prescribed ...
Castaneda, Javier, Cohen, Ohad, FILETTI, SEBASTIANO, Glandt, Mariela, MARANGHI, MARIANNA   +4 more
core   +2 more sources

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Treatment of Severe Hyperglycemia in Extremely Preterm Infants Using Continuous Subcutaneous Insulin Therapy

JCRPE
INTRODUCTION: Hyperglycemia in preterm infants is usually treated with adjustment of glucose intake and, if persistent, with continuous insulin infusion. However, hypoglycemia is a well-known complication of intravenous (iv) insulin treatment. The aim of
Merle Böettger, Tony Zhou, Jennifer Knopp, J. Geoffrey Chase, Axel Heep, Michael von Vangerow, Eva Cloppenburg, Matthias Lange   +7 more
doaj   +1 more source

Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations

Journal of Pharmaceutical Health Care and Sciences, 2019
Background Multiple daily subcutaneous injections (MDSIs) are mainly used for formulating an insulin therapy for diabetic patients; however, they also cause insulin-derived amyloidosis (IDA) and lead to poor glycemic control.
Yui Ohno, Tomohiro Seki, Yu Kojima, Ryotaro Miki, Yuya Egawa, Osamu Hosoya, Keizo Kasono, Toshinobu Seki   +7 more
doaj   +1 more source

In vivo investigation of the tissue response to commercial Teflon insulin infusion sets in large swine for 14 days: the effect of angle of insertion on tissue histology and insulin spread within the subcutaneous tissue. [PDF]

, 2019
Objective: This study investigated the effects of the inflammatory tissue response (ITR) to an insulin infusion set (IIS) on insulin bolus spread over wear time, as well as the effect of cannula insertion angle on the ITR, bolus shape, and pump tubing ...
Diaz, David, Dinesen, Alek R., Eisler, Gabriella, Joseph, Jeffrey I., Kastner, Jasmin R., Khalf, Abdurizzagh, Loeum, Channy, Strasma, Paul, Thakur, Mathew L., Torjman, Marc C.   +9 more
core   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

ОСОБЕННОСТИ НЕВРОЛОГИЧЕСКИХ ПРОЯВЛЕНИЙ САХАРНОГО ДИАБЕТА 1-го ТИПА ПРИ ИСПОЛЬЗОВАНИИ РАЗНЫХ МЕТОДОВ ИНСУЛИНОТЕРАПИИ

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
The study aimed to examine the features of neurological manifestations of diabetes mellitus type 1 by using insulin therapy with continuous subcutaneous infusion and multiple subcutaneous injections.

doaj  

Overcoming marked insulin resistance in a patient with type 2 diabetes mellitus by means of insulin pumptherapy

Сахарный диабет, 2012
Patients with type 2 diabetes mellitus (T2DM) often feature resistance to endogenous and exogenous insulin which is a serious problemto overcome. Current paper presents clinical case of T2DM characterized by marked insulin resistance, where high dosage ...
Ekaterina Viktorovna Artemova, Irina Vladimirovna Kononenko, Olga Mikhailovna Smirnova, Alexander Yur'evich Mayorov   +3 more
doaj   +1 more source

Comparison between continuous subcutaneous insulin infusion and multiple daily injection regimens in adolescent with type 1 diabetes from a public health care system approach to severe hypoglycemia [PDF]

, 2007
OBJECTIVE: We compared the incidence of severe hypoglycemia episodes with therapy with multiple doses of insulin (MDI) and after changing to pump (CSII).
Dib, Sergio Atala, Gabbay, Monica Andrade Lima   +1 more
core   +2 more sources

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source