Results 61 to 70 of about 35,220 (306)
PLoS ONE, 2021 The intraperitoneal route of administration accounts for less than 1% of insulin treatment regimes in patients with diabetes mellitus type 1 (DM1). Despite being used for decades, a systematic review of various physiological effects of this route of ...
Ilze Dirnena-Fusini +4 more
doaj +1 more source
Insulin Infusion Set: The Achilles Heel of Continuous Subcutaneous Insulin Infusion [PDF]
Journal of Diabetes Science and Technology, 2012 Continuous subcutaneous insulin infusion from an insulin pump depends on reliable transfer of the pumped insulin to the subcutaneous insulin depot by means of an insulin infusion set (IIS). Despite their widespread use, the published knowledge about IISs and related issues regarding the impact of placement and wear time on insulin absorption/insulin ...
Lutz, Heinemann, Lars, Krinelke
openaire +2 more sources
A new perspective on metformin therapy in type 1 diabetes [PDF]
, 2017 Metformin is quite frequently used off-label in type 1 diabetes to limit insulin dose requirement. Guidelines recommend that it can improve glucose control in those who are overweight and obese but evidence in support of this is limited.
Boyle, James G. +2 more
core +1 more source
Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis
Advanced Science, EarlyView.DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li +16 more
wiley +1 more source
From bench to bedside: Tracing the payback forwards from basic or early clinical research – A preliminary exercise and proposals for a future study [PDF]
, 2010 EXECUTIVE SUMMARY Chapter 1 : Introduction • The members of the research team from HERG and the Wellcome Trust have conducted previous studies showing that it is possible both to assess the payback from applied health research, and to use bibliometrics
Buxton, MJ +4 more
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Successful Management of a Patient with Florid Diabetic Retinopathy [PDF]
, 2016 Florid diabetic retinopathy is an unusual, aggressive type of diabetic retinopathy. It is seen in young patients with poor metabolic control. Despite advances in treatment the overall prognosis of this condition remains poor. A 21-year old female patient
Ahmad SS, Ghani SA, Alexander SM
core +1 more source
Advanced Science, EarlyView.In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li +15 more
wiley +1 more source
Journal of Medical Case Reports, 2012 Introduction Insulin allergy to human insulin preparations during the treatment of diabetes is suggested to occur at rates ranging from
Wheeler Benjamin J, Taylor Barry J
doaj +1 more source
Recommendations for Using Real-Time Continuous Glucose Monitoring (rtCGM) Data for Insulin Adjustments in Type 1 Diabetes. [PDF]
, 2017 The clinical benefits of real time continuous glucose monitoring (rtCGM) use have been well demonstrated in both CSII- and MDI-treated individuals in large clinical trials. However, recommendations for patient use of rtCGM in everyday life situations are
Edelman, Steven V, Pettus, Jeremy
core
Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model [PDF]
, 2011 The purpose of this study is to develop a rodent functional magnetic resonance imaging (fMRI) survival model with the use of heparin-coated vascular access devices.
Cho, Younghoon R +7 more
core +2 more sources