Results 71 to 80 of about 35,220 (306)

Brain‐Adhesive Bioelectronics With Shape‐Morphable and Biodegradable Properties for Stable Brain Signal Monitoring

Advanced Science, EarlyView.
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi, Soeun Kim, Sumin Kim, Jaehyun Park, Soojung An, Sungjun Yoon, Mikyung Shin, Sangho Cho, Donghee Son   +8 more
wiley   +1 more source

Successful management of severe diabetic ketoacidosis in a patient with type 2 diabetes with insulin allergy: a case report

BMC Endocrine Disorders, 2019
Background Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insulin.
Anh Dat Nguyen, Chinh Quoc Luong, Hieu Chi Chu, Van Khoa Dieu Nguyen, Chi Van Nguyen, Tuan Anh Nguyen, Quan Huu Nguyen, Ton Duy Mai, Dinh Van Nguyen, Bay Quang Nguyen, Thong Huu Tran, Phuong Viet Dao, Dat Tuan Nguyen, Nguyet Nhu Nguyen, Son Ngoc Do   +14 more
doaj   +1 more source

[Continuous subcutaneous insulin infusion].

Acta medica portuguesa, 2012
Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) represent two strategies of intensive insulin therapy, obtaining a strict metabolic control. The importance of such rigorous metabolic control in reducing the frequency and severity of diabetes long-term complications was highlighted by the Diabetes Control and ...
Ana Margarida, Balsa, Celestino, Neves, Marta, Alves, Miguel, Pereira, Davide, Carvalho, J Luís, Medina   +5 more
openaire   +1 more source

Estimation of nonlinear differential equation model for glucose-insulin dynamics in type I diabetic patients using generalized smoothing

, 2014
In this work we develop an ordinary differential equations (ODE) model of physiological regulation of glycemia in type 1 diabetes mellitus (T1DM) patients in response to meals and intravenous insulin infusion.
Apanasovich, Tatiyana V., Chervoneva, Inna, Freydin, Boris, Hipszer, Brian, Joseph, Jeffrey I.   +4 more
core   +1 more source

Comparative study of hormonal counterregulation during GCIIS-guided hypoglycemia tests using human Proinsulin and Human Insulin (recombinant DNA) [PDF]

, 1988
Schlechte ...
Ball, P., Bottermann, Peter, Henkel, E., Lühe, C. von der, Müller-Esch, G., Pfeiffer, E. F., Schlüter, K. J., Schlüter, K. J., Scriba, Peter Christian, Wood, W. G.   +9 more
core   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Artificial pancreas treatment for outpatients with type 1 diabetes: systematic review and meta-analysis. [PDF]

, 2018
OBJECTIVE: To evaluate the efficacy and safety of artificial pancreas treatment in non-pregnant outpatients with type 1 diabetes. DESIGN: Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES: Medline, Embase, Cochrane Library,
Athanasiadou, Eleni, Bekiari, Eleni, Haidich, Anna-Bettina, Hovorka, Roman, Karagiannis, Thomas, Kitsios, Konstantinos, Tauschmann, Martin, Thabit, Hood, Tsapas, Apostolos   +8 more
core   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

Continuous intraperitoneal insulin infusion as a valuable approach in patients with unstable type 1 diabetes: two case reports and a mini review of the literature

Frontiers in Medicine
In recent years, continuous intraperitoneal insulin infusion (CIPII) has become a valid therapeutic option to achieve good glycemic control for patients with unstable type 1 diabetes and subcutaneous insulin resistance, mainly due to the absorption of ...
Erika Pedone, Amelia Caretto, Giulio Belfiori, Anna Zanardini, Sergio Di Molfetta, Luigi Laviola, Francesco Giorgino, Lorenzo Piemonti, Lorenzo Piemonti, Lorenzo Piemonti, Marina Scavini, Andrea Laurenzi, Andrea Laurenzi   +12 more
doaj   +1 more source

Subcutaneous glucagon infusion and continuous glucose monitoring enable effective management of hypoglycemia in a patient with IGF-2-producing hemangiopericytoma

Clinical Diabetes and Endocrinology, 2018
Background Ectopic insulin-like growth factor (IGF)-2 production is a rare complication of an array of epithelial and mesenchymal tumors, and can clinically manifest as life-threatening hypoglycemia.
Eric D. Buras, Emily Weatherup, Jennifer Wyckoff   +2 more
doaj   +1 more source