Results 81 to 90 of about 35,220 (306)

Insulin/carbohydrates ratio during the first 6‐month therapy with insulin degludec in a paediatric population with type 1 diabetes previously treated with insulin glargine. An observational longitudinal study

Endocrinology, Diabetes & Metabolism, 2020
Background No data exist about the changes induced by the transition from first‐generation long‐acting insulins to second‐generation long‐acting analogues in the paediatric population.
Stefano Tumini, Olimpia Iacono, Laura Comegna, Elisabetta Fioretti, Paola Guidone, Gabriella Levantini, Daniele Panichi, Milena Catenaro, Ilaria Rossi, Flavia Amaro, Giusi Graziano, Maria Chiara Rossi, Paola Cipriano   +12 more
doaj   +1 more source

Emerging technologies for the management of Type 1 diabetes in pregnancy [PDF]

, 2018
Purpose of Review: The purpose of the study is to discuss emerging technologies available in the management of type 1 diabetes in pregnancy. Recent Findings: The latest evidence suggests that continuous glucose monitoring (CGM) should be offered to all ...
A Garcia-Patterson, A Weisman, AL Secher, AL Secher, C Farrington, D Bruttomesso, DN Voormolen, DS Feig, DS Feig, E Drever, E Wender-Ozegowska, EA Ryan, FM Moy, GR Law, GR Law, Helen R. Murphy, HR Murphy, HR Murphy, HR Murphy, HR Murphy, HR Murphy, HR Murphy, IM Evers, JC Pickup, Jennifer M. Yamamoto, JK Radder, K Cypryk, KJ Neff, M Berg, MJ Maresh, MM Kallas-Koeman, PD Ranasinghe, R Chen, R Fresa, R Worth, RJ Goudie, RM Bergenstal, RW Beck, SK Abell, TS Bailey, WV Tamborlane, ZA Stewart   +41 more
core   +2 more sources

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Development and validation of an instrument (CSII – Brazil) to assess users’ conceptual and procedural knowledge of continuous subcutaneous infusion systems

Archives of Endocrinology and Metabolism, 2020
Objective: To develop, adapt and validate an instrument named “CSII – Brazil” to assess users’ conceptual and procedural knowledge of continuous subcutaneous insulin infusion systems. Materials and methods: Methodological and exploratory study developed
Camilla Magalhães de Oliveira Amaral, Carla Ferraz de Oliveira Borges, Adriana Silvina Pagano, Aleida Nazareth Soares, Gabriela Franco Mourão, Janice Sepúlveda Reis   +5 more
doaj   +1 more source

The INCA System: A Further Step Towards a Telemedical Artificial Pancreas [PDF]

, 2008
Biomedical engineering research efforts have accomplished another level of a ldquotechnological solutionrdquo for diabetes: an artificial pancreas to be used by patients and supervised by healthcare professionals at any time and place.
Bergmann, Joachim, Bott, Oliver, Brugués, Eulalia, Dudde, Ralf, García Sáez, Gema, Gómez Aguilera, Enrique J., Hernando Pérez, María Elena, Leiva, Alberto de, Patte, Caroline, Peter, Pretschner, Rigla Cros, Mercedes, Schnell, Oliver, Vering, Thomas   +12 more
core   +3 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source

Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]

, 2014
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J, Harder, Helena, Jenkins, Valerie A, Stoner, Kelly L   +3 more
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Insulin pump therapy would be favored by pregnant women with diabetes

Cogent Psychology, 2020
To evaluate retrospectively the satisfaction of continuous subcutaneous insulin infusion (CSII) compared to multiple daily infusions in Japanese women with diabetes mellitus (DM) during pregnancy, we examined 27 women with type 1 (n = 20) or type 2 (n ...
Aya Osaki, Eijiro Yamada, Yasuyo Nakajima, Yuko Kasai, Yoko Shimoda, Akiko Toki, Kazuhiko Horiguchi, Satoshi Yoshino, Maki Inoue, Tsugumichi Saito, Takashi Kameda, Shuichi Okada, Masanobu Yamada   +12 more
doaj   +1 more source