Results 101 to 110 of about 16,132,005 (307)

Community pharmacy Medicines Use Review: current challenges

, 2018
Asam Latif School of Health Sciences, Queen’s Medical Centre, The University of Nottingham, Nottingham, UK Abstract: With a growing aging population, the appropriate, effective, and safe use of medicines is a global health policy priority.
Latif A
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Making Transfusion Medicine a Journey from Good to Great by Using Quality Indicators and Bringing in Continuous Quality Improvement

Global Journal of Transfusion Medicine, 2021
From its foundational years, transfusion medicine (TM) has been associated with errors and their reporting. Patient safety and quality were brought to the forefront of health care through the Institute of Medicine's two reports followed by the WHO (2004) forming a world alliance of 140 nations.
openaire   +2 more sources

National Medicines Information Centre VOLUME 24 NUMBER 4 2018

, 2018
Newsletter of the National Medicines Information CentreNo fundingLeinsterpeer ...
National Medicines Information Centre
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

National Medicines Information Centre VOLUME 24 NUMBER 3 2018

, 2018
Newsletter of the National Medicines Information CentreNo fundingLeinsterpeer ...
National Medicines Information Centre
core  

Improving antibiotic prescribing for children in the resource-poor setting. [PDF]

, 2015
Antibiotics are a critically important part of paediatric medical care in low- and middle-income countries (LMICs), where infectious diseases are the leading cause of child mortality. The World Health Organization estimates that >50% of all medicines are
Le Doare, Kirsty, Sharland, Mike, Sharland, M, Barker, CI, Irwin, A, Barker, Charlotte I. S., Irwin, Adam, Le Doare, K   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Factors influencing the functionality of medicines and therapeutic committees in public health facilities in Uganda: A longitudinal assessment.

PLoS ONE
World health organization estimates that of all medicines used globally, about 50% are used irrationally. This is mostly attributed to overuse of antibiotics and indiscriminate use of injectables, among other things.
Benard Nsubuga, Anthony Ddamba, Harriet Akello, David Arinaitwe, Phillip Ampaire, Moses Kamabare   +5 more
doaj   +1 more source

Migraine, monoclonal antibodies, and monitoring: a review of pharmacovigilance in the era of biologics

Frontiers in Pharmacology
Pharmacovigilance practices are essential for the rational use of medicines; this is even more true in the field of biologics. An ideal pharmacovigilance activity should cover all life phases of a drug to obtain more information on efficacy and safety by
Lorenza Guarnieri, Francesca Bosco, Maria Tiziana Corasaniti, Rita Citraro, Rita Citraro, Giovambattista De Sarro   +5 more
doaj   +1 more source