Results 101 to 110 of about 267,271 (334)

Identification of the benefits, enablers and barriers to integrating junior pharmacists into the ward team within one UK-based hospital

open access: yesIntegrated Pharmacy Research and Practice, 2017
Man Yui Hung,1 David John Wright,2 Jeanette Blacklock,2 Richard John Needle1,2 1Pharmacy Department, Colchester Hospital University NHS Foundation Trust, Colchester, 2School of Pharmacy, University of East Anglia, Norwich, UK Introduction: A high nurse ...
Hung MY   +3 more
doaj  

The use of complementary and alternative medicine is frequent in patients with pancreatic disorder [PDF]

open access: yes, 2016
BACKGROUND: Herbal remedies and other complementary and alternative medicine (CAM) are used by 30% of the patients with liver and inflammatory bowel diseases.
Archibugi, L   +4 more
core   +1 more source

Editorial: Towards continued and affordable accessibility of innovative drugs: sustainable development and efficient use of medicines

open access: yesFrontiers in Pharmacology
The rising cost of medicines burdens healthcare systems and limits access to novel therapies worldwide. Therefore, sustainable solutions to enhance access and foster innovation are crucial. To highlight current strategies and exchange ideas, we created a Research Topic titled “Towards continued and affordable accessibility of innovative drugs ...
Atse H. Huisman   +7 more
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Comparison of good review practices of seven countries participating in the ECOWAS medicines regulatory harmonisation initiative: identifying opportunities for improvement

open access: yesFrontiers in Medicine
IntroductionWhen implemented by national and regional regulatory agencies good review practices (GRevPs) support the timely high-quality review of medicines for enhanced patients’ availability to safe, quality and efficacious innovative and generic ...
Mercy Owusu-Asante   +19 more
doaj   +1 more source

Systems development: quality and safety of organic livestock products [PDF]

open access: yes, 2005
Overview of fourth SAFO Workshop: . Ninety-eight delegates from 19 countries attended the 4th SAFO Workshop. Previous Workshops had focused on the production system but the plenary papers at this meeting focused specifically on food quality and safety ...

core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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