Results 111 to 120 of about 16,132,005 (307)

Has Tanzania embraced the green leaf? Results from outlet and household surveys before and after implementation of the Affordable Medicines Facility-malaria. [PDF]

open access: yes, 2014
BACKGROUND: The Affordable Medicines Facility-malaria (AMFm) is primarily an artemisinin combination therapy (ACT) subsidy, aimed at increasing availability, affordability, market share and use of quality-assured ACTs (QAACTs).
Catherine Goodman   +71 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Irish Medicines Board seminar report: implications of the proposed interim national licencing scheme for traditional medicinal products

open access: yes, 2002
The Irish Medicines Board [IMB] hosted a seminar on the implications of the proposed interim national licensing scheme for traditional medicinal products at the Hilton Dublin Hotel on 2nd May 2002.
Irish Medicines Board (IMB)
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Antibiotics: A food safety issue [PDF]

open access: yesWestern Balkan Journal of Agricultural Economics and Rural Development, 2020
Population growth and globalization are currently having many negative effects on the agri-food sector's ability to ensure safe and qualitative food. Use of medicines and chemicals in animal husbandry can considerably increases production and animals ...
Stancu Alina, Suvorov Nicolae
doaj  

Irish Medicines Board fourth annual report to the Minister for Health and Children on the Irish Blood Transfusion Service (1st January to 31st December 2000) [PDF]

open access: yes, 2001
This is the fourth report to the Minister for Health & Children by the Irish Medicines Board (1MB) in relation to the Irish Blood Transfusion Service (IBTS). This organisation was previously known as The Blood Transfusion Service Board (BTSB).
Irish Medicines Board (IMB)
core  

Buyer beware? : does the information provided with herbal products available over the counter enable safe use? [PDF]

open access: yes, 2011
Background: Herbal products obtained over the counter are commonly used in Europe, North America and Australia. Although there is concern about a lack of information provided to consumers to allow the safe use of these products, there has been no ...
Nicolson Donald J   +19 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

What causes non-adherence among some individuals on long term antiretroviral therapy? Experiences of individuals with poor viral suppression in Uganda

open access: yesAIDS Research and Therapy, 2019
Background Antiretroviral therapy (ART) use by people living with HIV reduces HIV transmission, morbidity, mortality, and improves quality of life. Good ART adherence is required to achieve these benefits.
Dominic Bukenya   +4 more
doaj   +1 more source

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