Results 41 to 50 of about 4,252,456 (286)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Dual Cone Continuously Variable Transmission Model Controlled by LabVIEW

open access: yesMachines
This paper outlines the design, development, and practical implementation of a rubber belt-driven dual cone continuously variable transmission (CVT) model. This model enables a demonstration of stepless changes in the transmission ratio between input and
Šimon Berta   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Mechanics Analysis and Research of Multi- metal Belt in Automotive Continuously Variable Transmission

open access: yes, 2016
The continuously variable transmission can significantly improve the dynamic performance of automotive,which is the development direction of automobile transmission.
Wang Yunxia, Qi Xiaomin
core   +1 more source

Mechatronic Model of a Powertrain With Half Toroidal Continuously Variable Transmission

open access: yes, 2023
This paper presents a mechatronic model of a powertrain with a half toroidal continuously variable transmission. In this model, the actuator, the load on the output shaft, and the mechanical, electrical, and control dynamics are simultaneously considered.
Mendoza Trejo, Omar,   +3 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Motion Simulation of the Pulsing Mechanism of Continuously Variable Transmission based on Visual Basic

open access: yes, 2016
With the visual program design features of Visual Basic of being object- based and event-driven that contains integrated development environment,a motional simulation of the continuously variable transmission( CVT) pulsing mechanism is carried out,the ...
Xu Jianqiang   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Continuously Variable Transmissions - outline

open access: yesAUTOBUSY – Technika, Eksploatacja, Systemy Transportowe, 2018
Paper concerned the Continuously Variable Transmission (CVT). The comparison of the engine’s work conditions with conventional manual transmission and CVT’s is presented. Also, a short historical track is included. Furthermore, a production data with the forecast is presented for different parts of the World.
Bartosz Radzymiński, Jarosław Goszczak
openaire   +2 more sources

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