Results 51 to 60 of about 4,252,456 (286)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
An Experimental Study on Full Toroidal Continuously Variable Transmission System [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2011 : A continuously variable transmission (CVT) is a transmission which may change step less by way of an infinite variety of effective gear ratios between maximum and minimum values. This contrasts with different mechanical transmissions that solely permit
H. S. Patil
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Slip controller design and implementation in a continuously variable transmission [PDF]
Proceedings of the 2005, American Control Conference, 2005., 2005 Continuously Variable Transmissions (CVT) can be used to operate a combustion engine in a more optimal working point. Unfortunately, due to the relatively low efficiency of modern production CVT’s the total efficiency of the driveline is not increased significantly.
Pulles, R.J. +3 more
openaire +2 more sources
, 2022 In order to study the influence of multiple clutches on the transmission efficiency of a hydro-mechanical continuously variable transmission （HMCVT），the structure characteristics of a closed loop consisting of multiple wet friction clutches in the ...
Jianhua Wang +3 more
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Tribology Online, 2019 To improve the transmission efficiency of a continuously variable transmission (CVT) system, it is effective to form a tribofilm with higher friction coefficient.
Ayako Omura +8 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source