Results 81 to 90 of about 59,579 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Grid-point generation from contour images
, 2022 For Digital Elevation (DEM) generation, effective representation of the relationship between a required grid point and adjancent contours and the inter-relationship among these contours is necessary.
Tan, E.C., Chan, T.K., Zhu, C.
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Contour generation algorithm for Projection Mask Stereolithography 3D printing process [PDF]
, 2018 Projection mask stereolithography is a latest technology in 3D printing industry. It relies on UV projection to cure the photocurable resin layer-by-layer to build the solid 3D object.
Faeiz Azizi, Adnan, F. R. M., Romlay
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Trainable COSFIRE Filters for Keypoint Detection and Pattern Recognition [PDF]
, 2013 Background: Keypoint detection is important for many computer vision applications. Existing methods suffer from insufficient selectivity regarding the shape properties of features and are vulnerable to contrast variations and to the presence of noise or ...
Azzopardi, George, +6 more
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Automated gross tumor volume contour generation for large-scale analysis of early-stage lung cancer patients planned with 4D-CT. [PDF]
Med Phys, 2021 Davey A +4 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Comparison of 2nd generation LiDAR wind measurement technique with CFD numerical modelling
, 2012 With the rapid increase in both on and offshore wind turbine deployment there is a requirement for a better understanding of the flow field in which such devices are deployed.
Butler, Jonathan, Quail, Francis
core