Results 71 to 80 of about 138,300 (300)

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

Contributing factors to nonuptake of contraception among sexually active men in Asokore Mampong Municipality of Ghana: A cross-sectional study

Journal of Family Medicine and Primary Care
Background: The non-uptake of contraception by sexually active men is a significant health concern. However, there is a paucity of data concerning contraception use among sexually active men in Ghana. This study examined contributing factors to nonuptake
Hassana Haruna, Sam K. Newton, Maxwell O. Peprah, Fidelis Atibila, Charles Agyemang Prempeh, Tutuwaa B. Ewusie   +5 more
doaj   +1 more source

Another frontier for harm reduction: contraceptive needs of females who inject drugs in Estonia, a cross-sectional study

Harm Reduction Journal, 2018
Background Despite increasing contraceptive availability, unintended pregnancy remains a global problem. Developing strategies to reverse this trend and increasing occurrence of withdrawal syndrome among newborn children of females currently injecting ...
Anneli Uusküla, Mait Raag, Sigrid Vorobjov, Don Des Jarlais   +3 more
doaj   +1 more source

Contraception [PDF]

, 1985
Texto completo. Acesso restrito. p. 351–359A total of 189 women volunteered to accept subdermal implants for contraception. The implants were “covered rods”, consisting of a core rod containing equal parts by weight of levonorgestrel and ...
Pavez, Margarita, Coutinho, Elsimar Metzker, Croxatto, Horacio B., Paundes, Anibal, Stern, Janet, Diaz, Soledad, Holma, Pentti, Robertson, Dale N., Mishell Junior, Daniel Randolph, Brache, Vivian, Silva, Ana Rita da, Roy, Subir, Alvarez-Sanchez, Francisco, Sivin, Irving, Lacarra, Maria   +14 more
core  

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Contraception and health.

, 2012
Increasing contraceptive use in developing countries has cut the number of maternal deaths by 40% over the past 20 years, merely by reducing the number of unintended pregnancies.
Peterson, Herbert, Cleland, John, Conde-Agudelo, Agustin, Tsui, Amy, Ross, John   +4 more
core   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

A Novel Contraception Counseling and Shared Decision-Making Curriculum for Internal Medicine Residents

MedEdPORTAL, 2020
Introduction Many women of reproductive age with complex medical conditions receive primary care through an internal medicine (IM) physician rather than an obstetrician/gynecologist.
Rebeca Ortiz Worthington, Julie Oyler, Amber Pincavage, Nabil Abou Baker, Mark Saathoff, Jennifer Rusiecki   +5 more
doaj   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Journee de dialogue sur la contraception d\u27urgence (CU) [PDF]

, 2013
Le Population Council en collaboration avec le Consortium International sur la Contraception d’Urgence, a organisé, une journée de dialogue sur la contraception d’urgence (CU) au Sénégal, en partenariat avec le Ministère de la Femme, de l’Enfant et de l ...
Population Council, International Consortium for Emergency Contraception   +1 more
core   +1 more source