Results 121 to 130 of about 3,504,918 (198)

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Awake Blue Laser Excision and Balloon Dilation of Oropharyngeal Stenosis in High‐Risk Patients

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Oropharyngeal stenosis is a rare condition that can develop following head and neck cancer treatment, leading to progressive dyspnea, dysphagia, and dysphonia. Patients with symptomatic dyspnea may benefit from endoscopic surgery. However, head and neck cancer survivors can have severe trismus, limited neck extension, and altered laryngeal ...
Abbey L. Landini, Cyrus W. Abrahamson, Andrew P. Stein   +2 more
wiley   +1 more source

Therapeutic Interventions for Radiation‐Induced Fibrosis in Head and Neck Cancer Patients: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review and evaluate treatments for radiation‐induced fibrosis (RIF) following head and neck cancer (HNC) therapy. Data sources Medline, Embase.com, Web of Science, and Cochrane Library. Review Methods A systematic review was conducted on the management of HNC RIF using the Preferred Reporting Items for Systematic Reviews and Meta ...
Pooja D. Reddy, Purva Rumde, Vanessa Helou, Mary L. Klem, Matthew E. Spector, Marci L. Nilsen, Kevin J. Contrera   +6 more
wiley   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 3—One Center's Evolving Regional Anesthesia Experience and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery is the dominant model of surgical care in the U.S. and has impacted the practice of regional anesthesia (RA). Pediatric RA's use has expanded as a supplement to general anesthesia with the introduction of ultrasound.
David E. Liston, Elizabeth E. Hansen, Jennifer L. Chiem, Sean H. Flack, Daniel K. W. Low, Lynn D. Martin   +5 more
wiley   +1 more source

Beyond denomination: The relationship between religion and family planning in rural Malawi [PDF]

Despite the centrality of religion and fertility to life in rural Africa, the relationship between the two remains poorly understood. The study presented here uses unique integrated individual- and congregational-level data from rural Malawi to examine ...
Sara Yeatman, Jenny Trinitapoli
core  

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source

Desired fertility and the impact of population policies [PDF]

Ninety percent of the differences across countries in total fertility rates are accounted for solely by differences in women's reported desired fertility.
Pritchett, Lant H., DEC
core