Results 41 to 50 of about 3,504,918 (198)

Refractory chronic urticaria and angioedema associated with a CVID-like immune dysregulation phenotype in an adolescent: A multisystem management challenge [PDF]

Journal of Preventive and Complementary Medicine
Background: Chronic idiopathic urticaria (CIU), also referred to as chronic spontaneous urticaria, is characterized by recurrent wheals with or without angioedema persisting for more than six weeks.
Thy Nguyen, Drew Johnston, Zafar Qureshi, Ochuko Onoberhie, Syed Rizvi   +4 more
doaj   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Neem-natural contraceptive for male and female-an overview

, 2011
Neem has been used traditionally as a medicine for various ailments. It has been reported to possess wound healing, antiviral, antiarthritic, anti-hyper glycemic and anti-inflammatory properties and also help in curing skin diseases. A novel use of neem (
Jyotsna A Saonere Suryawanshi
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

Advanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen, Meihong Liu, Mengchao Ding, Ye Liu, Chuanxu Zhu, Mingye Gong, Zhixuan Huang, Yi Zhang, Wei Xue, Youyong Yuan, Kewei Wang   +10 more
wiley   +1 more source

Clinical behavior of a cohort of adult women with facial acne treated with combined oral contraceptive: ethinylestradiol 20 µg/dienogest 2 mg

International Journal of Women's Health, 2017
John Palacio-Cardona,1 Diana María Caicedo Borrero2 1Student Welfare Service – Health Area, Santiago de Cali University, 2Support for Research, Academic, Scientific and Technological Services (SEACIT), Cali, Colombia Abstract: Acne ...
Palacio-Cardona J, Caicedo Borrero DM
doaj  

“The Doctor Helped Me Decide”: A Linguistic Analysis of Contraceptive Shared Decision-Making Narratives in Clinical Encounters Supported by a Decision Aid Mobile Application

Perspectives on Medical Education
Introduction: Shared decision-making, in which a patient’s values and preferences facilitate the co-construction of a clinical decision, is a key component of patient-centered care and is of pedagogical interest in medical training.
Catherine T. Witkop, Lauren A. Maggio, Abigail Konopasky   +2 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Contraceptive Method Choice Among Women Attending at Amtullabhai Family Planning Clinic in Dar es salaam [PDF]

, 2011
Contraceptive prevalence in Tanzania is low despite high knowledge of contraception. In order to understand the existing barriers, it is important to find out reasons affecting contraceptive method choices.
Mbando, Apaisaria Humphrey, Mbando, Apaisaria H   +1 more
core