Results 161 to 170 of about 3,363,257 (386)

EudraVigilance insights: Suspected adverse drug reactions in infants through breastfeeding

British Journal of Clinical Pharmacology, EarlyView.
Aims We aimed to describe suspected adverse drug reactions (ADRs) in infants resulting from medications transmitted through mothers' milk, as reported to the European ADR database, EudraVigilance. The research sought to understand the frequency, seriousness and nature of these ADRs to assess potential risks associated with maternal medication use ...
Ida M. Heerfordt, Ditte Resendal Gotfredsen, Henrik Horwitz, Anette Kirstine Stark, Jon Trærup Andersen, Christina Gade, Ulrik Lausten‐Thomsen, Rasmus Huan Olsen   +7 more
wiley   +1 more source

Enhancing the use of family planning service statistics using a Bayesian modelling approach to inform estimates of modern contraceptive use in low- and middle-income countries [PDF]

arXiv
Monitoring family planning indicators, such as modern contraceptive prevalence rate (mCPR), is essential for family planning programming. The Family Planning Estimation Tool (FPET) uses survey data to estimate and forecast family planning indicators, including mCPR, over time.
arxiv  

Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the effect of a potent cytochrome P450 (CYP) 3A inhibitor and CYP inducer on the pharmacokinetics of ritlecitinib, a JAK3/TEC family kinase inhibitor, and assess the effect of ritlecitinib on the pharmacokinetics of CYP substrates (midazolam, efavirenz, tolbutamide, caffeine and oral contraceptives [ethinyl oestradiol and levonorgestrel])
Vivek S. Purohit, Yeamin Huh, Martin E. Dowty, Anna Plotka, Alexandre Lejeune, Hindu Kalluru, Brian Hee   +6 more
wiley   +1 more source

Pharmacology and relevant drug interactions of metamizole

British Journal of Clinical Pharmacology, EarlyView.
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
David J. Brinkman, Linda C. Hendriksen, Irma M. Rigter, Markus W. Hollmann   +3 more
wiley   +1 more source

Fertility awareness, perceived factors and approaches to improve contraceptive uptake among sexually active adolescent girls in Phalombe, Malawi: a mixed-methods study

Reproductive Health
Background Healthcare practitioners and policymakers in Sub-Saharan Africa face a significant health challenge due to the insufficient fertility awareness and other perceived health outcomes in contraceptive use among adolescent girls.
Precious L. Hajison, Felistas Mpachika-Mfipa, Lerato Pitso, Lumbani Tshotetsi, Chancy Skenard Chimatiro   +4 more
doaj   +1 more source

Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health

BioEssays, EarlyView.
The microfluidic Cervix Chip is an in vitro model of the human cervix lined by cervical epithelium interfaced with stromal cells cultured under dynamic flow that represents a new preclinical platform for studying mucosal immunity, host‐microbiome interactions, infections, fertility, and pregnancy health.
Zohreh Izadifar, Anna Stejskalova, Aakanksha Gulati, Ola Gutzeit, Donald E. Ingber   +4 more
wiley   +1 more source

EFFECTS OF CONTRACEPTIVE AGENTS ON DRUG METABOLISM IN VARIOUS ANIMAL SPECIES [PDF]

, 1976
G. Briatico, Giovanna Guiso, A. Jori, C Ravazzani   +3 more
openalex   +1 more source

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

Cancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang, Qingyuan Zhang, Tao Sun, Huiping Li, Ying Cheng, Zhongsheng Tong, Huihui Li, Wei Li, Jingfen Wang, Yuee Teng, Xinhong Wu, Jing Cheng, Zhendong Chen, Zhengqiu Zhu, Li Wang, Mingming Liu, Xianghui Duan, Lingmei Xu, Binghe Xu   +18 more
wiley   +1 more source

Double‐vestibular incision subperiosteal tunnel access (double‐VISTA) with connective tissue graft for treating multiple gingival recessions: 2‐year follow‐up

Clinical Advances in Periodontics, EarlyView.
Abstract Background Gingival recession has a multifactorial etiology, involving various predisposing and precipitating factors. Non‐carious cervical lesions (NCCLs) are often associated with gingival recession and pose challenges due to their complex pathodynamics.
Guo‐Hao Lin
wiley   +1 more source

Consideraciones sobre planificación familiar: métodos anticonceptivos

Revista Cubana de Medicina General Integral, 2001
Resumen Se realizó una revisión histórica sobre el desarrollo de cada uno de los métodos anticonceptivos que pueden ser usados como medios para evitar los embarazos no deseados y poder tener una adecuada planificación familiar.
Ignacio González Labrador, Emilia Miyar Pieiga   +1 more
doaj