Results 1 to 10 of about 6,199 (160)

Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman [PDF]

open access: yesAcute Medicine & Surgery
Aim The overdose of caffeine, a cytochrome P450 1A2 probe, in young women has become a problem. The aim of this study was to evaluate possible drug interactions between intentionally overdosed caffeine (12 g) and oral contraceptive doses of ethinyl ...
Koichiro Adachi   +6 more
doaj   +2 more sources

Bioequivalence study of low dose drospirenone/ethinyl estradiol 3 mg/0.03 mg film tablets under fasting conditions in Turkish healthy female subjects [PDF]

open access: yesPharmacology Research & Perspectives
This bioequivalence research aims to evaluate the relative bioavailability and pharmacokinetic characteristics of ethinyl estradiol and drospirenone in the test preparation in comparison to the reference preparation during fasting conditions.
Ahmet Inal   +7 more
doaj   +2 more sources

Effects of the selective AMPA modulator NBI‐1065845 on the pharmacokinetics of midazolam or ethinyl estradiol–levonorgestrel in healthy adults [PDF]

open access: yesClinical and Translational Science
This parallel‐arm, phase I study investigated the potential cytochrome P450 (CYP)3A induction effect of NBI‐1065845 (TAK‐653), an investigational α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor potentiator in phase II development for major ...
Swan Lin   +6 more
doaj   +2 more sources

Comparing the risk of deep vein thrombosis of two combined oral contraceptives: Norethindrone/ethinyl estradiol and drospirenone/ethinyl estradiol [PDF]

open access: yesHeliyon
Background: Deep vein thrombosis (DVT) has been reported as an adverse event for patients receiving combined oral contraceptives. Norethindrone/ethinyl estradiol (NET/EE) and drospirenone/ethinyl estradiol (DRSP/EE) are two commonly prescribed combined ...
Jennifer Stalas   +8 more
doaj   +2 more sources

Effectiveness and safety assessment of drospirenone/ethinyl estradiol tablet in treatment of PCOS patients: a single center, prospective, observational study [PDF]

open access: yesBMC Women's Health, 2020
Background To investigate the effectiveness and safety of 3 mg drospirenone and 20 μg ethinyl estradiol tablet (3 mg DRSP/20 μg EE) in the treatment of polycystic ovary syndrome (PCOS).
Li Li   +12 more
doaj   +2 more sources

Determination of ethinyl estradiol and levonorgestrel in human plasma with prednisone as internal standard using ultra-performance liquid chromatography–tandem mass spectrometry

open access: yesJournal of Pharmacy and Bioallied Sciences, 2019
Objective: Ethinyl estradiol and levonorgestrel as a combination of oral contraceptive drugs have very low dosage levels; hence, a highly sensitive and selective method of using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS)
Yahdiana Harahap   +2 more
doaj   +2 more sources

Pharmaceutical-technological aspects of therapeutic systems for hormonal contraception [PDF]

open access: yesArhiv za farmaciju, 2016
The use of therapeutic systems for hormonal contraception (TSHC) represents an important alternative approach for prevention of unintended pregnancies in comparison to oral hormonal contraceptives, whereby the risk of gastrointestinal adverse effects ...
Đekić Ljiljana, Primorac Marija
doaj   +1 more source

Regulation of hepatic apolipoprotein synthesis in the 17 alpha-ethinyl estradiol-treated rat.

open access: yesJournal of Lipid Research, 1991
Regulatory mechanisms of hepatic apolipoprotein synthesis were studied in groups of male Sprague-Dawley rats made severely hypolipidemic by treatment with pharmacological doses of 17 alpha-ethinyl estradiol.
M Seishima   +3 more
doaj   +1 more source

Information on the combined hormonal contraceptives (CHC) containing the dienogest + ethinyl estradiol combination (Jeanine®)

open access: yesАкушерство, гинекология и репродукция, 2019
In this short communication, the editorial board publishes the information on safety of the combined hormonal contraceptive (CHC) Jeanine®, containing the fixed dose combination of dienogest and ethinyl estradiol.
A. D. Makatsariya   +3 more
doaj   +1 more source

Impact of Ethinyl Estradiol to Human Telomerase Reverse Transcriptase Activity on Complete Hydatidiform Mole Culture

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2016
Objective: To prove the effect of ethinyl estradiol as an activator on human Telomerase Reverse Transcriptase (hTERT). Method: The experimental study was conducted in vitro by using culture of complete hydatidiform mole trophoblast cell.
Tatit Nurseta   +2 more
doaj   +1 more source

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