Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman [PDF]
Aim The overdose of caffeine, a cytochrome P450 1A2 probe, in young women has become a problem. The aim of this study was to evaluate possible drug interactions between intentionally overdosed caffeine (12 g) and oral contraceptive doses of ethinyl ...
Koichiro Adachi +6 more
doaj +2 more sources
Bioequivalence study of low dose drospirenone/ethinyl estradiol 3 mg/0.03 mg film tablets under fasting conditions in Turkish healthy female subjects [PDF]
This bioequivalence research aims to evaluate the relative bioavailability and pharmacokinetic characteristics of ethinyl estradiol and drospirenone in the test preparation in comparison to the reference preparation during fasting conditions.
Ahmet Inal +7 more
doaj +2 more sources
Effects of the selective AMPA modulator NBI‐1065845 on the pharmacokinetics of midazolam or ethinyl estradiol–levonorgestrel in healthy adults [PDF]
This parallel‐arm, phase I study investigated the potential cytochrome P450 (CYP)3A induction effect of NBI‐1065845 (TAK‐653), an investigational α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor potentiator in phase II development for major ...
Swan Lin +6 more
doaj +2 more sources
Comparing the risk of deep vein thrombosis of two combined oral contraceptives: Norethindrone/ethinyl estradiol and drospirenone/ethinyl estradiol [PDF]
Background: Deep vein thrombosis (DVT) has been reported as an adverse event for patients receiving combined oral contraceptives. Norethindrone/ethinyl estradiol (NET/EE) and drospirenone/ethinyl estradiol (DRSP/EE) are two commonly prescribed combined ...
Jennifer Stalas +8 more
doaj +2 more sources
Effectiveness and safety assessment of drospirenone/ethinyl estradiol tablet in treatment of PCOS patients: a single center, prospective, observational study [PDF]
Background To investigate the effectiveness and safety of 3 mg drospirenone and 20 μg ethinyl estradiol tablet (3 mg DRSP/20 μg EE) in the treatment of polycystic ovary syndrome (PCOS).
Li Li +12 more
doaj +2 more sources
Objective: Ethinyl estradiol and levonorgestrel as a combination of oral contraceptive drugs have very low dosage levels; hence, a highly sensitive and selective method of using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS)
Yahdiana Harahap +2 more
doaj +2 more sources
Pharmaceutical-technological aspects of therapeutic systems for hormonal contraception [PDF]
The use of therapeutic systems for hormonal contraception (TSHC) represents an important alternative approach for prevention of unintended pregnancies in comparison to oral hormonal contraceptives, whereby the risk of gastrointestinal adverse effects ...
Đekić Ljiljana, Primorac Marija
doaj +1 more source
Regulation of hepatic apolipoprotein synthesis in the 17 alpha-ethinyl estradiol-treated rat.
Regulatory mechanisms of hepatic apolipoprotein synthesis were studied in groups of male Sprague-Dawley rats made severely hypolipidemic by treatment with pharmacological doses of 17 alpha-ethinyl estradiol.
M Seishima +3 more
doaj +1 more source
In this short communication, the editorial board publishes the information on safety of the combined hormonal contraceptive (CHC) Jeanine®, containing the fixed dose combination of dienogest and ethinyl estradiol.
A. D. Makatsariya +3 more
doaj +1 more source
Objective: To prove the effect of ethinyl estradiol as an activator on human Telomerase Reverse Transcriptase (hTERT). Method: The experimental study was conducted in vitro by using culture of complete hydatidiform mole trophoblast cell.
Tatit Nurseta +2 more
doaj +1 more source

