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Estrogen and estrogen receptors in kidney diseases [PDF]

Renal Failure, 2021
Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
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Estrogen, Estrogen Receptor and Lung Cancer [PDF]

International Journal of Molecular Sciences, 2017
Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
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Estrogens and environmental estrogens

Biomedicine & Pharmacotherapy, 2002
The natural female sex hormone estrogens binds once inside the cell to a protein receptor to form a 'ligand-hormone receptor complex'. The binding activates the hormone receptor, which triggers specific cellular processes. The activated hormone receptor then turns on specific genes, causing cellular changes that lead to responses typical of a ligand ...
H, Tapiero, G Nguyen, Ba, K D, Tew
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The binding of estrogen and estrogen antagonists to the estrogen receptor

Archives of Biochemistry and Biophysics, 1992
The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
J P, Bond, S, Sasson, A C, Notides
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Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Beatrice E. Bachmeier, Ulrich Pfeffer, Killian, Peter H., Blengio, Fabiola, Valentina Mirisola, Romeo, Francesco, Dell'Eva, Raffaella, Pfeffer, Ulrich, Luca Generoso, Fabiola Blengio, Alessia Esposito, Raffaella Dell’Eva, Mirisola, Valentina, Generoso, Luca, Albini, Adriana, Adriana Albini, Peter H. Killian, Bachmeier, Beatrice E., Esposito, Alessia, Francesco Romeo   +19 more
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Single-cell states in the estrogen response of breast cancer cell lines [PDF]

, 2014
Estrogen responsive breast cancer cell lines have been extensively studied to characterize transcriptional patterns in hormone-responsive tumors. Nevertheless, due to current technological limitations, genome-wide studies have typically been limited to ...
Andrea Gamba, Nassa, Giovanni, Roberto Amendola, Mario Nicodemi (81682), Sach Mukherjee (19432), Chris J Oates, Francesco Paolo Casale (526999), Nicodemi, M, Weisz, Alessandro, Gamba, A, Jonathan, W., Alessandro Weisz (90872), Alessandro Weisz, Giorgio Giurato (527000), Giorgio Giurato, Gamba, Andrea, Cora', Davide, Chris J. Oates, Gamba, Andrea Antonio, Armond, Jonathan W., Weisz, A, Amendola, Roberto, Mukherjee, Sach, Casale, Francesco Paolo, Oates, Chris J., Jonathan W. Armond, Mario Nicodemi, Oates, CJ, Giovanni Nassa, Davide Corá, Nassa, G, Corá, Davide, Ro Weisz, Mukherjee, S, Giovanni Nassa (527001), Chris J. Oates (527003), Francesco Paolo Casale, Giurato, Giorgio, Andrea Gamba (181217), Nicodemi, Mario, Sach Mukherjee, Davide Cor?, Giurato, G, Corá, D, Chris, J., Jonathan W Armond, Davide Corá (5649682), Armond, JW, Jonathan W. Armond (527002), Casale, FP   +49 more
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Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]

, 2013
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo, Claudia Colussi (377816), Luis Jaime Castro-Vega (409816), Londono-Vallejo Arturo, Londono-Vallejo, Arturo, Simona Nanni, Colussi Claudia, Nanni, Simona, Pontecorvi, Alfredo, Castro-Vega, Luis Jaime, Carlo Gaetano (110837), Capogrossi, Maurizio C., Re, Agnese, Silvia Bacchetti (409817), Aiello Aurora, Valentina Benvenuti (409815), Guffanti Alessandro, Felsani, Armando, Claudia Colussi, Simona Nanni (110816), Maurizio C Capogrossi, Felsani Armando, Bacchetti, Silvia, Luis Jaime Castro-Vega, Benvenuti, Valentina, Armando Felsani (132772), Re Agnese, Pontecorvi Alfredo, Antonella Farsetti, Alessandro Guffanti, Gaetano, Carlo, Armando Felsani, Agnese Re, Castro-Vega Luis Jaime, Arturo Londono-Vallejo (5654743), Aurora Aiello, Nanni Simona, Alessandro Guffanti (5573), Maurizio C. Capogrossi (103525), Gaetano Carlo, Carlo Gaetano, Agnese Re (409814), Aurora Aiello (358824), Guffanti, Alessandro, Farsetti Antonella, Farsetti, Antonella, Capogrossi Maurizio C., Alfredo Pontecorvi, Alfredo Pontecorvi (409818), Antonella Farsetti (110827), Silvia Bacchetti, Aiello, Aurora, Benvenuti Valentina, Bacchetti Silvia, Colussi, Claudia, Valentina Benvenuti   +55 more
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Estrogen-Independent Activation of Estrogen Receptors [PDF]

Hypertension, 2011
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Barton, Matthias, Meyer, Matthias R., Prossnitz, Eric R.   +2 more
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Molecular mechanism of estrogen–estrogen receptor signaling [PDF]

Reproductive Medicine and Biology, 2016
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin, Ayaz, Gamze, User, Sirma Damla, Gupur, Gizem, Muyan, Mesut   +4 more
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Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]

, 2003
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE, Stephen S. Nussey, Whitley, GS, Guy St J. Whitley, Holden, DP, Desmond P. Holden, Nussey, SS, Judith E. Cartwright   +7 more
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