Results 31 to 40 of about 484,589 (309)

Hysterectomy for Benign Indications and Risk of Cataract Formation in South Korean Women

open access: yesMedicina, 2023
Background and Objectives: Few studies have investigated the relationship between female reproductive hormones, especially estrogen, and the incidence of cataracts.
Jae Suk Kim
doaj   +1 more source

Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]

open access: yes, 2013
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo   +58 more
core   +2 more sources

Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain

open access: yesFrontiers in Endocrinology, 2012
Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
doaj   +1 more source

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone

open access: yesMolecules, 2023
Estradiol (E2) plays an important role in the progression of diseases such as breast cancer and endometriosis. Inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1), the enzyme that catalyzes the last step in the biosynthesis of the estrogenic
Adrien Djiemeny Ngueta   +3 more
doaj   +1 more source

Signaling by estrogens [PDF]

open access: yesJournal of Cellular Physiology, 2007
AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J, Cheskis   +3 more
openaire   +2 more sources

Field and laboratory approaches to assess "estrogen disruption" in the brown trout "Salmo trutta" [PDF]

open access: yes, 2008
In recent years, the annual catches of brown trout and other native fish species have been declining in Switzerland about 60%. One hypothesis was that the reduced catch is linked to estrogen-active chemicals entering the aquatic environment via waste ...
Körner, Oliver
core   +1 more source

Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview

open access: yesCells
The endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman’s life based on estrogen and progesterone fluctuations.
Isabelle Dias Da Silva   +3 more
doaj   +1 more source

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen [PDF]

open access: yes, 2012
SynthSys is a Centre for Integrative Systems Biology (CISB) funded by BBSRC and EPSRC, reference BB/D019621/1.Background: Estrogen receptors alpha (ER) are implicated in many types of female cancers, and are the common target for anti-cancer therapy ...
Harrison, David J   +12 more
core   +1 more source

Weak if any effect of estrogen on spatial memory in rats [PDF]

open access: yes, 2002
In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Németh, Hajnalka   +5 more
core   +1 more source

A rapidly enlarging cutaneous hemangioma in pregnancy

open access: yesClinics and Practice, 2014
This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient’s thumb during her pregnancy. This was excised and identified as a hemangioma.
Marwan Ma’ayeh   +3 more
doaj   +1 more source

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