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Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Reproductive Medicine and Biology, 2016 Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin +4 more
openaire +3 more sources
Estrogenic Activities in Rodent Estrogen-Free Diets [PDF]
Endocrinology, 2005 Diets lacking soy and alpha-alpha derivatives that are considered to be estrogen-free by standard bioassays (uterotrophic assay and vaginal opening) have been revealed to contain considerable amounts of compounds able to transcriptionally activate the estrogen receptors (ERs) and stimulate luciferase expression in several organs of the ERE-Luc reporter
P. Ciana +5 more
openaire +3 more sources
Association between sex steroid hormones and subsequent hyperglycemia during pregnancy
Frontiers in Endocrinology, 2023 ObjectiveSex steroid hormones may play a role in insulin resistance and glucose dysregulation. However, evidence regarding associations between early-pregnancy sex steroid hormones and hyperglycemia during pregnancy is limited.
Ying Meng +17 more
doaj +1 more source
Estrogen receptor as the predictive factor for response to chemotherapy in breast cancer [PDF]
Archive of Oncology, 2006 It has generally been accepted that breast cancer (BC) cells are equally responsive to chemotherapy (CHT) irrespective of ER status. However, subset analyses of disease outcome in recently reported trials on neoadjuvant and adjuvant CHT brought new ...
Šušnjar Snežana +1 more
doaj +1 more source
Developmental Effects of Prenatal Exposure to Bisphenol A on the Uterus of Rat Offspring
Neoplasia: An International Journal for Oncology Research, 2004 Exposure to estrogenic compounds during critical periods of fetal development could result in adverse effects on the development of reproductive organs that are not apparent until later in life.
Gilbert Schönfelder +3 more
doaj +1 more source
Hysterectomy for Benign Indications and Risk of Cataract Formation in South Korean Women
Medicina, 2023 Background and Objectives: Few studies have investigated the relationship between female reproductive hormones, especially estrogen, and the incidence of cataracts.
Jae Suk Kim
doaj +1 more source
Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain
Frontiers in Endocrinology, 2012 Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
doaj +1 more source
Molecules, 2023 Estradiol (E2) plays an important role in the progression of diseases such as breast cancer and endometriosis. Inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1), the enzyme that catalyzes the last step in the biosynthesis of the estrogenic
Adrien Djiemeny Ngueta +3 more
doaj +1 more source
Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview
CellsThe endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman’s life based on estrogen and progesterone fluctuations.
Isabelle Dias Da Silva +3 more
doaj +1 more source
A rapidly enlarging cutaneous hemangioma in pregnancy
Clinics and Practice, 2014 This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient’s thumb during her pregnancy. This was excised and identified as a hemangioma.
Marwan Ma’ayeh +3 more
doaj +1 more source