Results 41 to 50 of about 430,922 (218)

Estrogens and atherosclerosis [PDF]

European Journal of Endocrinology, 2004
Numerous epidemiological as well as experimental studies have suggested that estradiol (E2) prevents atherosclerosis development. However two controlled prospective and randomized studies in women using hormone replacement therapy (HRT) did not confirm this beneficial effect. We then decided to use mouse models of atherosclerosis to define the possible
J-F, Arnal, P, Gourdy, R, Elhage, B, Garmy-Susini, E, Delmas, L, Brouchet, C, Castano, Y, Barreira, J C, Couloumiers, H, Prats, A-C, Prats, F, Bayard   +11 more
openaire   +2 more sources

Impact of sex hormones on postoperative outcomes in plastic surgery: a narrative review

Frontiers in Surgery
BackgroundSince 1929, when scientists first identified estrogen in urine and coined the term “sex hormones,” these vital steroid hormones have been recognized for their critical role in tissue repair and wound healing. This is particularly evident in the
Xiong Lv, Chun Xiang, Yan Zheng, Xuling Lv, Wanxuan Zhou, Jiajun Zhu   +5 more
doaj   +1 more source

Elevated p53 promotes the processing of miR-18a to decrease estrogen receptor-alpha in female hepatocellular carcinoma

, 2017
The estrogen pathway has long been implicated as a tumor protector in female hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Our previous study identified that estrogen receptor alpha (ER) protein is downregulated in 60% of female HCC ...
陳定信;葉坤輝;葉秀慧;陳培哲;陳祈玲, Li, Chiao-Ling;Yeh, Kun-Huei;Liu, Wan-Hsin;Chen, Chi-Ling;Chen, Ding-Shinn;Chen, Pei-Jer;Yeh, Shiou-Hwei   +1 more
core   +1 more source

The Women's international study of long-duration oestrogen after menopause (WISDOM): a randomised controlled trial [PDF]

, 2007
Background: At the time of feasibility work and final design of the trial there was no randomised control trial evidence for the long-term risks and benefits of hormone replacement therapy.
Knott, C., Taylor, L., Tom W Meade, Welton, A., Meade, T., Vickers Madge R, Vickers, M., Meredith, S., Prince, M., Meade Tom W, Gordon, E., Huppert, F., Martin Jeannett, Meade, Tom W, Furness, P., Martin, J., Purdon, S., Martin, Jeannett, Collins, N., Ghali, M., Islam, Z., Vickers, Madge R, WISDOM study team, Arasaratnum, N., null null, Jeannett Martin, Walgrove, A., Wilkes, H., Ford, D., et al., Richards, M., Madge R Vickers   +31 more
core   +1 more source

Expression Profiles of Estrogen-Regulated MicroRNAs in Breast Cancer Cells

, 2016
Molecular signaling through both estrogen and microRNAs are critical for breast cancer development and growth. The activity of estrogen is mediated by transcription factors, the estrogen receptors. Here we describe a method for robust characterization of
Cecilia Williams, Katchy, A, Williams, C,, Williams, Cecilia,, Katchy, Anne, Anne Katchy   +5 more
core   +1 more source

Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer [PDF]

, 2010
In women with estrogen receptor(ER)- and ErbB2(HER2)-positive breast cancer, a vicious cycle is established between ER mechanisms of action and the growth factor receptor network, leading to enhanced cell proliferation and endocrine resistance.
Bauerfeind, Ingo, Elling, Dirk, Heinemann, Volker   +2 more
core   +1 more source

Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study

Frontiers in Neurology
BackgroundHigh-dose testosterone replacement therapy (TRT), paired with finasteride (type II 5α-reductase inhibitor), improves body composition, muscle strength, and bone mineral density (BMD) in older men, without inducing prostate enlargement—a side ...
Dana M. Otzel, Dana M. Otzel, Larissa Nichols, Christine F. Conover, Stephen A. Marangi, Jayachandra R. Kura, Dominic K. Iannaccone, David J. Clark, David J. Clark, Chris M. Gregory, Christopher F. Sonntag, Anita Wokhlu, Anita Wokhlu, Hans K. Ghayee, Michael J. McPhaul, Charles E. Levy, Charles A. Plumlee, Charles A. Plumlee, Robert B. Sammel, Robert B. Sammel, Kevin T. White, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow   +24 more
doaj   +1 more source

Letrozole Administration as a New Way of Regulating Reproductive Activity in Female Quail

Journal of Applied Poultry Research, 2019
SUMMARY: We investigated the effects of letrozole as a contraceptive on egg production and serum sex hormones in laying quails. Several female reproductive disorders are the most common causes that require stopping egg production in laying and breeding ...
Nesar Zandi, Amjad Farzinpour, Asaad Vaziry   +2 more
doaj   +1 more source

Age and estrogen-associated reductions in hypoxic ventilatory response and chemosensitivity in female rats

Frontiers in Physiology
Respiratory function is modulated by circulating steroid hormones. In female rats, steroid hormones fluctuate across the normal estrous cycle and decline with age, similar to human menopause.
Jessica M. L. Grittner, Rebecca Barok, Edgar Juarez Lopez, Misha Shah, Brendan J. Dougherty   +4 more
doaj   +1 more source

SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24+ CD49fhi Mammary Stem Cell-Enriched Compartment

Stem Cell Reports, 2017
Estrogen stimulates breast development during puberty and mammary tumors in adulthood through estrogen receptor-α (ERα). These effects are proposed to occur via ERα+ luminal cells and not the mammary stem cells (MaSCs) that are ERαneg. Since ERα+ luminal
Genevieve V. Dall, Jessica L. Vieusseux, Kenneth S. Korach, Yukitomo Arao, Sylvia C. Hewitt, Katherine J. Hamilton, Elaine Dzierzak, Wah Chin Boon, Evan R. Simpson, Robert G. Ramsay, Torsten Stein, Joanne S. Morris, Robin L. Anderson, Gail P. Risbridger, Kara L. Britt   +14 more
doaj   +1 more source