Sex-dependent influence of endogenous estrogen in pulmonary hypertension [PDF]
, 2014 Rationale: The incidence of pulmonary arterial hypertension (PAH) is greater in women suggesting estrogens may play a role in the disease pathogenesis. Experimentally, in males exogenously administered estrogen can protect against PH; however in models ...
Audrey F. Wright +17 more
core +1 more source
Estrogen, Estrogen Receptor and Lung Cancer [PDF]
International Journal of Molecular Sciences, 2017 Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
openaire +2 more sources
Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview
CellsThe endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman’s life based on estrogen and progesterone fluctuations.
Isabelle Dias Da Silva +3 more
doaj +1 more source
Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
, 2010 Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
core +1 more source
Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Reproductive Medicine and Biology, 2016 Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin +4 more
openaire +3 more sources
Phytochemical Assessment on N-hexane Extract and Fractions of Marsilea Crenata Presl. Leaves Through Gc-ms [PDF]
, 2016 Estrogen deficiency causes various health problems in postmenopausal women, including osteoporosis. Phytoestrogen emerged as a potential alternative of estrogen with minimum side effects.
Agil, M. (Mangestuti) +2 more
core +4 more sources
Estrogenic Activities in Rodent Estrogen-Free Diets [PDF]
Endocrinology, 2005 Diets lacking soy and alpha-alpha derivatives that are considered to be estrogen-free by standard bioassays (uterotrophic assay and vaginal opening) have been revealed to contain considerable amounts of compounds able to transcriptionally activate the estrogen receptors (ERs) and stimulate luciferase expression in several organs of the ERE-Luc reporter
P. Ciana +5 more
openaire +3 more sources
Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells. [PDF]
, 2012 Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.
Fu, Lei +6 more
core +1 more source
A rapidly enlarging cutaneous hemangioma in pregnancy
Clinics and Practice, 2014 This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient’s thumb during her pregnancy. This was excised and identified as a hemangioma.
Marwan Ma’ayeh +3 more
doaj +1 more source
Estrogenic activity, race/ethnicity, and Indigenous American ancestry among San Francisco Bay Area women. [PDF]
, 2019 Estrogens play a significant role in breast cancer development and are not only produced endogenously, but are also mimicked by estrogen-like compounds from environmental exposures.
Fejerman, Laura +6 more
core +2 more sources