Results 31 to 40 of about 6,240 (179)

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas   +3 more
wiley   +1 more source

Dissociation of bile flow and biliary lipid secretion from biliary lysosomal enzyme output in experimental cholestasis.

open access: yesJournal of Lipid Research, 1981
Although the cellular mechanisms controlling bile flow and biliary lipid secretion are unclear, morphologic data suggest that intracellular vesicles may be involved.
V H Lopez del Pino, N F LaRusso
doaj   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert   +2 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Biological Sex Differences in Sleep Spindles and Slow Wave Activity in Adults With and Without Insomnia

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Mounting evidence shows sex‐based differences in sleep experiences and outcomes, including the prevalence of insomnia disorder. However, the impact of biological sex on brain oscillations during sleep remains poorly understood, especially in the context of insomnia disorder. This is a notable gap, given that neurophysiological aspects of sleep
Nyissa A. Walsh   +5 more
wiley   +1 more source

Development of a highly sensitive reporter gene cell line for detecting estrogenic activity (the ER Isjaki assay)

open access: yesEnvironment International
Monitoring of estrogens in water sources faces significant challenges, as proposed changes in the European Union regulation for environmental protection of water bodies, compromise the ability of conventional analytical methods to detect low ...
Aline Colonnello Montero   +3 more
doaj   +1 more source

Association of Systemic Hormonal Contraceptives With Reconstruction Procedures for Patellar Instability

open access: yesOrthopaedic Journal of Sports Medicine, 2023
Background: Previous research suggests that estrogen plays a role in increased ligamentous laxity observed within the female population. Whereas many studies have sought to evaluate the impact of exogenous estrogen on anterior cruciate ligament injuries,
Brandon J. Martinazzi MD   +6 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory   +13 more
wiley   +1 more source

Advances in contraception: vaginal contraceptive rings

open access: yesTherapeutic Advances in Reproductive Health, 2023
The vaginal contraceptive ring is very effective and user dependent. In this article, we will discuss the different types of vaginal contraceptive rings, namely, the etonogestrel/ethinyl estradiol (ENG/EE) ring (NuvaRing, Merck, Rahway, NJ, USA) and the ...
Sara Al-Haddad   +2 more
doaj   +1 more source

Evaluation of a Point‐of‐Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus)

open access: yesJournal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Introduction Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia. Materials and Methods Twelve bonobos from one institution were evaluated during anesthetized exams.
Megan M. Roeder   +7 more
wiley   +1 more source

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