Results 31 to 40 of about 22,954 (265)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Determinants of subdermal contraceptive use among women of reproductive age: A Cross-Sectional Study

Jurnal Ilmiah Kesehatan Sandi Husada
Introduction: Family planning is a key global public health strategy to reduce maternal morbidity and mortality. The World Health Organization (WHO) reports that millions of women of reproductive age worldwide still have unmet needs for modern ...
Dahniar, Uliarta Marbun, Lili Purnama Sari, Irnawati, Arisna Kadir   +4 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Chronic stress associated to contraceptives use on the progression of ligature-induced periodontitis in rats

Revista de Odontologia da UNESP
Introduction Contraceptives are widely used by women in much of the world. The stress associated with their use can lead adverse responses in the body.
Débora Prado MARTINS, Tereza Aparecida Delle Vedove SEMENOFF, Álvaro Henrique BORGES, Natalino Francisco da SILVA, Alex SEMENOFF-SEGUNDO   +4 more
doaj   +1 more source

Phylogenetic Diversity and Susceptibility of Candida Species from Women using Contraceptive Devices in Central Nigeria

International Journal of Infectious Diseases, 2022
Purpose: The use of contraceptive devices predisposes women to vulvovaginal candidiasis globally. Despite the high incidence of vulvovaginal candidiasis and antifungal resistance to azoles, the genetic diversity and resistance pattern among contraceptive
A. Lillian, A. Chuku, N. Joseph, B. Ajide, R. Reuben, O. Akwashiki   +5 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Alteraciones prenatales y conocimientos sobre riesgos biosociales en embarazadas adolescentes

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: el embarazo en edades cada vez más tempranas se está convirtiendo en un problema social y de salud pública de alcance mundial.Objetivo: caracterizar el conocimiento de las embarazadas adolescentes sobre los riesgos biosociales en la gestación
Mayde González Crúz, Mirna León Acebo, Mayra Lourdes Pérez Nápoles, Jorge Luis Pérez Manzano, Liudmila Aponte Ramirez   +4 more
doaj