Results 41 to 50 of about 1,571,650 (304)

Phylogenetic Diversity and Susceptibility of Candida Species from Women using Contraceptive Devices in Central Nigeria

International Journal of Infectious Diseases, 2022
Purpose: The use of contraceptive devices predisposes women to vulvovaginal candidiasis globally. Despite the high incidence of vulvovaginal candidiasis and antifungal resistance to azoles, the genetic diversity and resistance pattern among contraceptive
A. Lillian, A. Chuku, N. Joseph, B. Ajide, R. Reuben, O. Akwashiki   +5 more
doaj   +1 more source

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

Arthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang, Qai Ven Yap, Peter Pak Moon Cheung, Amelia Santosa, Gim Gee Teng   +4 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Prevalence and inequalities in contraceptive use among adolescents and young women: data from a birth cohort in Brazil

Cadernos de Saúde Pública, 2021
Monitoring trends of contraceptive use and identifying the groups with less coverage are needed to guide public policies and make them more efficient. But, in Brazil, recent data about these aspects are limited.
Adriana Kramer Fiala Machado, Débora Dalmas Gräf, Fabiane Höfs, Franciele Hellwig, Karoline Sampaio Barros, Laísa Rodrigues Moreira, Pedro Augusto Crespo, Mariângela Freitas Silveira   +7 more
doaj   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Ultrasound-Guided Hydrodissection with Needle Stabilization: An Innovative Nerve-Sparing Approach to Remove a Contraceptive Implant Causing Ulnar Neuropathy

Diagnostics
Background and Clinical Significance: Non-palpable migrated contraceptive implants pose significant challenges for removal and are associated with neurovascular complications.
Yeui-Seok Seo, HoWon Lee, Jihyo Hwang, Chanwool Park, MinJae Lee, Yonghyun Yoon, HyeMi Yu, Jaeik Choi, Gyungseog Ko, Daniel Chiung-Jui Su, Keneath Dean Reeves, Teinny Suryadi, Anwar Suhaimi, King Hei Stanley Lam   +13 more
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Alteraciones prenatales y conocimientos sobre riesgos biosociales en embarazadas adolescentes

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: el embarazo en edades cada vez más tempranas se está convirtiendo en un problema social y de salud pública de alcance mundial.Objetivo: caracterizar el conocimiento de las embarazadas adolescentes sobre los riesgos biosociales en la gestación
Mayde González Crúz, Mirna León Acebo, Mayra Lourdes Pérez Nápoles, Jorge Luis Pérez Manzano, Liudmila Aponte Ramirez   +4 more
doaj  

Psychometric Properties of a Measure Assessing Attitudes and Norms as Determinants of Intention to Use Oral Contraceptives

Asian Nursing Research, 2015
Purpose: Asian immigrant and Asian American women are less likely to use oral contraceptives (OCs) and tend to rely on low-efficacy methods of contraception.
Jongwon Lee, PhD, RN, Mauricio Carvallo, PhD, Taehun Lee, PhD   +2 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source