Results 51 to 60 of about 3,161,306 (342)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Games, 2022 In this study, we enrich a standard principal–agent model with hidden action by introducing salience-biased perception on the agent’s side. The agent’s misguided focus on salient payoffs, which leads the agent’s and the principal’s probability ...
Fabio Römeis +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Journal of Field OrnithologyHabitat specialists, impacted by anthropogenic land modification, are often of great conservation concern. Florida Scrub-Jays ( Aphelocoma coerulescens ) are threatened, scrub-endemic birds primarily found in small, isolated patches where they have a ...
Cory J Spern +4 more
doaj +1 more source
THE CHARACTERISTICS OF REED LIGHTWEIGHT CLAY BRICKS AFTER DRYING PROCESS
International Islamic University Malaysia Engineering Journal, 2020 The drying procedure is one of the basic stages in the brick making process, particularly when utilizing the extrusion framing technique. This stage decides the quality and amount of the brick samples.
Ghazwan Abdulsamad Salman Algburi
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Liver lipid response to intravenous rare earths in rats
Journal of Lipid Research, 1959 Intravenous injection of rare earths with low atomic numbers produces fatty infiltration in the liver of rats. This infiltration is maximal 48 hours later and is characterized by an increase in neutral fat esters.
Fred Snyder +2 more
doaj +1 more source
European Journal of Privacy Law & Technologies, 2022 Il saggio affronta la delicata questione della necro-robotica e le sue implicazioni etico-giuridiche. Il contributo, inoltre, si concentra sull'analisi della normativa in materia di protezione dei dati personali post mortem e sulla loro disponibilità ...
Remo Trezza
doaj +1 more source
Perceived Effects of Prevalent Errors in Contract Documents on Construction Projects [PDF]
, 2018 One of the highly rated causes of poor performance is errors in contract documents. The objectives of this study are to investigate the prevalent errors in contract documents and their effects on construction projects.
Dosumu, Oluwaseun Sunday
core +3 more sources