Results 61 to 70 of about 3,161,306 (342)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Photodynamic Inactivation of Foodborne Bacteria: Screening of 32 Potential Photosensitizers

open access: yesFoods
The development of novel antimicrobial technologies for the food industry represents an important strategy to improve food safety. Antimicrobial photodynamic disinfection (aPDD) is a method that can inactivate microbes without the use of harsh chemicals.
Amritha Prasad   +10 more
doaj   +1 more source

Contracts in Practice [PDF]

open access: yes, 2013
Contracts are a form of lightweight formal specification embedded in the program text. Being executable parts of the code, they encourage programmers to devote proper attention to specifications, and help maintain consistency between specification and ...
A. Wasylkowski   +10 more
core   +4 more sources

Retractable Contracts [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
In Proceedings PLACES 2015, arXiv:1602 ...
Barbanera Franco   +3 more
openaire   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Efficacy of a Lidocaine-Impregnated Elastrator Band for Castration and Tail Docking in Lambs

open access: yesAnimals
The primary objective of this study was to demonstrate the non-inferiority between lidocaine-impregnated ligation bands (LLBs) and control bands (CBs) with respect to the efficacy of castration and tail docking.
Steven M. Roche   +9 more
doaj   +1 more source

Efficacy of a proprietary formulation of fipronil/(S)-methoprene/cyphenothrin against Ixodes scapularis tick infestations on dogs

open access: yesParasites & Vectors, 2015
Background Efficacy of FRONTLINE® TRITAK® For Dogs (fipronil/(S)-methoprene/cyphenothrin, Merial, Inc., Duluth, GA) against Ixodes scapularis was evaluated in two separate, but concurrent laboratory studies.
Doug Carithers   +3 more
doaj   +1 more source

A New Contract [PDF]

open access: yes, 1996
Jeremiah 31:32 ...
Mills, Michael
core   +1 more source

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