Results 221 to 230 of about 244,667 (356)

Revealing the biophysics of lamina-associated domain formation by integrating theoretical modeling and high-resolution imaging. [PDF]

Nat Commun
Dhankhar M, Guo Z, Kant A, Basir R, Joshi R, Vinayak V, Heo SC, Mauck RL, Lakadamyali M, Shenoy VB.   +9 more
europepmc   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

The Plasticizer Dibutyl Phthalate (DBP) Impairs Pregnancy Vascular Health: Insights into Calcium Signaling and Nitric Oxide Involvement. [PDF]

J Xenobiot
Quelhas AR, Mariana M, Cairrao E.
europepmc   +1 more source

A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation [PDF]

, 2018
et al,, Mann, Douglas L
core   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

Inhibition of Contractility of Isolated Caprine Detrusor by the Rho Kinase Inhibitor Fasudil and Reversal by the Guanylyl Cyclase Inhibitor ODQ. [PDF]

Curr Ther Res Clin Exp
Jeeviha NJ, Kumar A, Mathew RA, Joseph S, Haris M, Shanthi M, Peedicayil J.   +6 more
europepmc   +1 more source

Investigating A Dose Response Relationship between High Fat Diet Consumption and the Contractile Performance of Isolated Mouse Soleus, EDL and Diaphragm Muscles [PDF]

, 2019
A Abdelmoula, A Matsakas, A Wronska, BH Goodpaster, C Barclay, C Barclay, Cameron Hill, CJ Blimkie, CJ Tanner, D Akhmedov, D Pette, D Tomlinson, DM D’Souza, DS Ward, F Zurlo, FR Paolillo, H Eshima, J Aucouturier, J Ciapaite, J Kemp, J Machann, J Mendez, J Szymura, J Tallis, J Tallis, J Tallis, J Tallis, J Tallis, J Wilde de, Jason Tallis, JD Altringham, JD Bruton, Josh Hurst, KE Shortreed, KE Trajcevski, M Hulens, MA Brotto, MM Thomas, MS Denies, N Miyatake, NA Maffiuletti, NA Maffiuletti, P Capodaglio, P Kopelman, P Rogers, R Singh, RK Josephson, RK Josephson, Rob S. James, RS James, RS James, RS James, S Warmington, SR Anderson, Val M. Cox, Y Rolland, Y Yoshida   +56 more
core   +1 more source

ULTRASTRUCTURAL STUDIES ON THE CONTRACTILE MECHANISM OF SMOOTH MUSCLE [PDF]

, 1969
Robert E. Kelly, Robert V. Rice
openalex   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source

Neuro‐Cancer Interactions Shape Glioma Intratumoral Heterogeneity

Advanced Science, EarlyView.
This review proposes a conceptual framework for understanding glioma intratumoral heterogeneity shaped by neuro‐cancer interactions: functional patterns and transcriptional states. Functional patterns manifest as three major neural‐like adaptations with spatial and potentially hierarchical relationships, including neurogliomal synapses, glioma networks,
Tong Wu, Peiran Zhao, Zheng Chen, Tianlei Ying, Zhihong Nie, Wei Hua, Huiyan Li, Ying Mao, Wenbo Bu   +8 more
wiley   +1 more source