Results 221 to 230 of about 254,999 (359)

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Role of purinergic activation and TRPC3 channels in the Frank-Starling mechanism. [PDF]

J Physiol Sci
Chiba Y, Kaihara K, Iribe G.
europepmc   +1 more source

The effects of neuropeptide Y on myocardial contractility and coronary blood flow [PDF]

, 1991
Sonia J. Awad, Rosemarie Einstein, Erica K. Potter, D.P. Richardson   +3 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Quantitative assessment of the usability of electromechanical human-based modelling and simulation to replace Langendorff isolated rabbit heart experiments in the preclinical setting. [PDF]

Front Pharmacol
Holmes M, Martinez-Navarro H, Mohr M, Chambard JM, Ballet V, Vermersch E, Garry A, Schmidt F, Rodriguez B.   +8 more
europepmc   +1 more source

Cardiac contractility, motor function, and cross‐bridge kinetics in N47K‐RLC mutant mice [PDF]

, 2017
Li Wang, Katarzyna Kaźmierczak, Chen‐Ching Yuan, Sunil Kumar Yadav, Masataka Kawai, Danuta Szczesna‐Cordary   +5 more
openalex   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Postoperative efficacy of transurethral resection of the prostate (TURP) in treating benign prostatic hyperplasia combined with detrusor underactivity. [PDF]

Medicine (Baltimore)
Xin Y, Li D, Lin S, Gan R, Li L, Zhao Z, Zhao A, Yang C, Li B.   +8 more
europepmc   +1 more source

Acute methamphetamine exposure inhibits cardiac contractile function

, 2009
Subat Turdi, Robbie M. Schamber, Nathan D. Roe, Herbert G. Chew, Bruce Culver, Jun Ren   +5 more
openalex   +1 more source

Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle. [PDF]

, 1988
Roderick MacKinnon, Judith K. Gwathmey, Paul D. Allen, George M. Briggs, James P. Morgan   +4 more
openalex   +1 more source