Results 281 to 290 of about 244,667 (356)

Changes in hemodynamics of pulmonary artery using Flowire in a canine model of acute pulmonary thromboembolism

Animal Models and Experimental Medicine, EarlyView.
This study investigated changes in pulmonary artery hemodynamics using a Flowire catheter and evaluated the accuracy of Doppler echocardiography in dogs with acute pulmonary thromboembolism (PTE). Ten healthy beagles were anesthetized, and acute pulmonary hypertension (PH) was induced by injecting 300‐μm dextran microspheres.
Tomohiko Yoshida, Katsuhiro Matsuura, Akiko Uemura, Ryou Tanaka   +3 more
wiley   +1 more source

Cardiac Contractility Modulation as bridge to recovery in a patient with advanced heart failure evaluated for left ventricular assist devices: a case report and review of literature. [PDF]

Front Cardiovasc Med
Menichetti F, Solari M, Salvetti E, Guarnaccia V, Girasole T, Venturi F, Del Rosso A.   +6 more
europepmc   +1 more source

Development, validation, and preliminary phenotypic characterization of a Col6a3 knockout mouse model targeting exon 3

Animal Models and Experimental Medicine, EarlyView.
Deleting Col6a3 exon 3 by CRISPR in mice results in centralized nuclei consistent with a myopathy phenotype mimicking collagen VI‐associated human disease Abstract Background Most mutations in the COL6A3 gene lead to collagen VI‐related myopathies. This is due to a reduced expression or mislocalization of the COL6A3 protein.
Michel ElChoueiry, Harsimran Sidhu, Maude Lévesque, Dominique Lévesque, Jean‐François Jacques, Otman Sarrhini, Jean‐François Beaudoin, Molly Caron, Brenda Gaudette, Roger Lecomte, Xavier Roucou, François‐Michel Boisvert, Jean‐Philippe Brosseau   +12 more
wiley   +1 more source

Investigating the Anrep Effect in Hypertrophic Obstructive Cardiomyopathy With Invasive Pressure-Volume Analysis. [PDF]

JACC Adv
Reil JC, Sequeira V, Reil GH, Scholtz S, Rudolph V, Maack C, Serruys P, Steendijk P.   +7 more
europepmc   +1 more source

Bioprinting‐Assisted Tissue Assembly to Investigate Endothelial Cell Contributions in Cardiac Fibrosis and Focal Fibrosis Modeling

Advanced NanoBiomed Research, EarlyView.
GA: Bioprinting‐assisted tissue assembly, a method for generating versatile and complex tissue constructs, is employed to investigate the contribution of endothelial cells (ECs) in cardiac fibrosis. ECs modulate fibrotic responses not only by preventing significant tissue stiffening and contractile impairment but also by exhibiting endothelial‐to ...
Dong Gyu Hwang, Hwanyong Choi, Myungji Kim, Minji Kim, Donghwan Kim, Jinseon Park, Jinah Jang   +6 more
wiley   +1 more source

Conceptualizing myocardial contractility as an emergent property that characterizes myocardial contraction. [PDF]

Front Physiol
Kuang SY, Geloian G.
europepmc   +1 more source

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

Advanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang, Jann Harberts, Yaping Chen, Richard J. Williams, Wei Duan, Rasika M. Samarasinghe, Nicolas H. Voelcker, Roey Elnathan   +7 more
wiley   +1 more source

Junctional force patterning drives both positional order and planar polarity in the auditory epithelia. [PDF]

Nat Commun
Prakash A, Weninger J, Singh N, Raman S, Rao M, Kruse K, Ladher RK.   +6 more
europepmc   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source