Results 281 to 290 of about 254,999 (359)

ZSF1 lean rats – How healthy are they?

Animal Models and Experimental Medicine, EarlyView.
This study aimed to examine the health status, specifically the physiology and myocardial, vascular, and skeletal muscle function of lean ZSF1 rats by comparing them to age‐ and sex‐matched Wistar rats. Compared to Wistar controls, ZSF1 lean rats exhibited lower body weight, but showed increased heart, and skeletal muscle mass.
Antje Schauer, Beatrice Vahle, Volker Adams, Axel Linke, Antje Augstein   +4 more
wiley   +1 more source

Cardiac Aftermath of Gestational Diabetes-From Intrauterine Impact to Lifelong Complications: A Systematic Review. [PDF]

J Dev Biol
Tsokkou S, Konstantinidis I, Keramas A, Anastasiou V, Matsas A, Florou M, Arvanitaki A, Peteinidou E, Karamitsos T, Giannakoulas G, Dagklis T, Papamitsou T, Ziakas A, Kamperidis V.   +13 more
europepmc   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

Comparing the Efficacy of Myosin Inhibition Versus Thin Filament Calcium Desensitization for Treatment of Pediatric Restrictive Cardiomyopathy Using a Patient-Derived hiPSC Model. [PDF]

Circ Genom Precis Med
Staudt DW, Serrano R, Hnatiuk AP, Sanchez I, Carhuamaca X, Feyen DAM, Mercola M.   +6 more
europepmc   +1 more source

CEMIP Maintains Vascular Contractility by Controlling PP1c-MLC20 Cascade in SMCs

Ze Yuan, Qi Li, Xue Bai, Kai Zhang, Jinlong He, Ding Ai, Qinghua Cui, Yi Zhu, Bochuan Li   +8 more
openalex   +1 more source

GPR18 Deletion in Mice Inversely Affects Vasoactive Signaling and Passive Biomechanical Properties of the Thoracic Aorta and Femoral Artery. [PDF]

Int J Mol Sci
De Moudt S, Herzine A, Rodrigues ML, Collin M, Bäck M, Yen FT, Mercier N.   +6 more
europepmc   +1 more source

Investigation of image-guided in vivo irradiation on voiding patterns and bladder contractility in female mice. [PDF]

Sci Rep
McDowell S, Breen C, McKerr N, Srivastava K, Crummey D, Ghita-Pettigrew M, Butterworth KT, O'Sullivan JM, Prise KM, McCloskey KD.   +9 more
europepmc   +1 more source

Myosin 2 drives actin contractility in fast-crawling species outside of the amorphean lineage. [PDF]

Curr Biol
Guest SL, Velle KB, Jacques SM, Park Y, Man J, Titus MA, Fritz-Laylin LK.   +6 more
europepmc   +1 more source