Results 71 to 80 of about 1,628 (305)

On Fixed Points of α-ψ-Contractive Multivalued Mappings in Cone Metric Spaces

open access: yesAbstract and Applied Analysis, 2013
We define the notion of α*-ψ-contractive mappings for cone metric space and obtain fixed points of multivalued mappings in connection with Hausdorff distance function for closed bounded subsets of cone metric spaces.
Marwan Amin Kutbi   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Convergence and well-posedness properties of uniformly locally contractive mappings

open access: yes, 2023
In a 1961 paper by E. Rakotch it was shown that a uniformly locally contractive mapping has a fixed point. In the present paper we show that for such a mapping, the fixed point problem is well posed and that inexact iterates of such a mapping converge
Reich, Simeon, Zaslavski, Alexander J.
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

NEW FIXED POINT RESULTS FOR T-CONTRACTIVE MAPPING WITH c-DISTANCE IN CONE METRIC SPACES [PDF]

open access: yes, 2020
In this article, we generalize and improve the results of Fadail et al.[Z. M. Fadail and S. M. Abusalim, Int. Jour. of Math. Anal., Vol. 11, No. 8(2017), pp. 397-405.] and Dubey et al.[AnilKumar Dubey and Urmila Mishra, Non. Func. Anal. Appl., Vol.
Pandey, Mithilesh Deo   +3 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Weakly Contractive Mapping and Weakly Kannan Mapping in Partial Metric Space

open access: yes, 2019
In the article the concept of metric space could be expanded, one of which is a partial metric space. In the metric space, the distance of a point to itself is equal to zero, while in the partial metric space need not be equal to zero.The concept of ...
Sadjidon, S.   +2 more
core   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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