Results 41 to 50 of about 1,076,694 (286)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Dialetheism and Metaphor

Studies in Logic, Grammar and Rhetoric, 2020
In the paper two seemingly distinct areas of philosophical investigations are brought together: metaphor and dialetheism. They both turn out to be deeply related, which becomes visible against a background, i.e.
Rybarkiewicz Dorota
doaj   +1 more source

Information technology and gender equality: a contradiction in terminis? [PDF]

, 1997
Using the data source of the Computers in Education (Comped) study, carried out under the auspices of the International Association for the Evaluation of Educational Achievement (IEA), the status of gender and computer use in education in a number of ...
Janssen Reinen, Ingeborg, Plomp, Tjeerd
core   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

CONTRADICTIONS IN PEDAGOGICAL RESEARCH. AN ANALYSIS FROM A DIALECTICAL-MATERIALIST CONCEPTION OF THE WORLD / LAS CONTRADICCIONES EN LAS INVESTIGACIONES PEDAGÓGICAS. UN ANÁLISIS DESDE LA CONCEPCIÓN DIALÉCTICO-MATERIALISTA DEL MUNDO

Didasc@lia: didáctica y educación, 2012
This article is aimed at clarifying the dynamic in précising and identifying the contradictions in scientific investigations, especially in the field of Pedagogical Sciences, from a dialectical-materialist conception of the world.
Ernan Santiesteban Naranjo, Kenia María Velázquez Ávila   +1 more
doaj  

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

The Philosophy of Ecology and Sustainability: New Logical and Informational Dimensions

Philosophies, 2018
Ecology and sustainability are current narratives about the behavior of humans toward themselves and the environment. Ecology is defined as a science, and a philosophy of ecology has become a recognized domain of the philosophy of science.
Joseph E. Brenner
doaj   +1 more source

Peculiarities of the influence of conflict culture and personal competence on the confrontational modus operandi in conflict relations

Вестник университета, 2022
The article analyses the problems of the formation of conflict interactions and relationships caused by the influence of conflictological culture and competence of the individual, which in recent years has become a priority.
N. I. Pryanikova
doaj   +1 more source