Results 31 to 40 of about 188,355 (251)
TRIZ method for innovation applied to an hoverboard
Cogent Engineering, 2018 The aim of this work is to complete the QFD analysis carried out in a previous work that aimed to identify the main features that contribute to the success of a modern urban transport means: the hoverboard.
Giampiero Donnici +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
How Does Asef-Mohseni Act While Facing with Najāshī’s and Ṭūsī’s Contradictions [PDF]
تحقیقات علوم قرآن و حدیث, 2019 Najāshī and Sheikh Ṭūsī are among the most well-known Shiite biographers (rijālīs), whose rijālī views were of great importance of consideration, especially following the establishment of the Hilla School and the improvement of Hadith validation on the ...
Majid Zeidi-Joudaki +3 more
doaj +1 more source
, 2023 Face aux mutations de la production et de la gestion urbaine, de plus en plus ancrées dans le contexte du néolibéralisme urbain, des pratiques « alternatives » émergent.
Les contradictions urbaines de la participation +1 more
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
eJournal de la Recherche sur l'Intervention en Éducation Physique et SportMichel Serres entitled his latest book (2020), “I Thank the Physical Education Teachers for Teaching Me to Think”, and what if physical education was or would be this cornerstone that allows reflexivity ?
Elise Houssin
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source