Results 101 to 110 of about 82,694 (258)

Contrast induced nephropathy after transcatheter aortic valve implantation

Alʹmanah Kliničeskoj Mediciny, 2017
Background: Aortic stenosis ranks the third in the structure of all cardiovascular diseases, conceding only to arterial hypertension and coronary heart disease.
D. L. Kranin, V. V. Stets, O. R. Pestovskaya, E. P. Dunaev, D. A. Nazarov, A. V. Gaydukov, G. V. Mashtanov, K. S. Zamskiy, A. Yu. Fedorov, K. A. Varochkin, S. A. Kurnosov   +10 more
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Glycemic Regulation and Renal Function by Heavy Metal Exposure: A Cross‐Sectional Analysis on Cement Plant Workers

Journal of Applied Toxicology, EarlyView.
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan, Fatma Bozdag, Fatıma Betül Topcu, Osman Burak Demirbas, Sultan Pinar Cetintepe, Mustafa Necmi Ilhan   +5 more
wiley   +1 more source

Contrast-induced nephropathy - prevention and treatment

Quality in Sport
Introduction and purpose: Contrast-induced nephropathy (CIN) is kidney damage that can occur after the administration of contrast agents used in medical imaging procedures like angiography and CT scans. The exact mechanism is not fully understood but is
Mateusz Bajak, Julia Słowik, Daniel Zapasek, Michał Szczepański, Maciej Mamczur, Dominik Maciej Feret, Jadwiga Inglot, Julia Inglot, Marcin Kuliga, Damian Sowa, Katarzyna Widawska   +10 more
doaj   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Comparison of Low‐Iodine Concentration Quantification Accuracy and Contrast‐To‐Noise Ratio Across Three Dual‐Energy CT Techniques: A Phantom Study

Journal of Medical Radiation Sciences, EarlyView.
Using a clinical abdominal CT protocol, all three DECT techniques accurately quantified iodine. Rapid kV‐switching achieved the lowest detectable and quantifiable iodine concentrations, while dual‐layer DECT provided the highest normalised contrast‐to‐noise ratio on 40‐keV virtual monoenergetic images.
Chonsitron Sirituenlee, Sirapasson Kraison, Paweena Wongpan, Pawitiya Supawarapong, Teeraphat Pataraphitakpong, Supannika Kawvised, Samrit Kittipayak, Monchai Phonlakrai   +7 more
wiley   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

JEADV Clinical Practice, EarlyView.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri, Marta Dechant, Tilo Biedermann   +2 more
wiley   +1 more source