Results 41 to 50 of about 49,984 (235)

THE RATE OF RENAL DYSFUNCTION IN PATIENTS WITH ACUTE CORONARY SYNDROME AFTER USING X-RAY CONTRAST AGENTS

Медицинский вестник Юга России, 2015
Purpose: to evaluate the rate and severity of filtration renal dysfunction in patients with acute coronary syndrome after percutaneous coronary intervention (PCI) with X-ray contrast.Materials and Methods: serum creatinine levels were collected from 71 ...
N. T. Vatutin, M. I. Zinkovych
doaj   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Circulating MicroRNA‐188, ‐30a, and ‐30e as Early Biomarkers for Contrast‐Induced Acute Kidney Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundContrast‐induced acute kidney injury (CI‐AKI) is typically defined by an increase in serum creatinine after intravascular administration of contrast medium.
Shi‐qun Sun, Tuo Zhang, Ding Ding, Wei‐feng Zhang, Xiao‐lei Wang, Zhe Sun, Liu‐hua Hu, Sheng‐ying Qin, Ling‐hong Shen, Ben He   +9 more
doaj   +1 more source

Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Assessing contrast-induced nephropathy risk in older adults undergoing coronary angiography and intervention: The CV/GFR ratio versus Mehran score

SAGE Open Medicine
Background: Contrast-induced nephropathy is a prevalent cause of hospital-acquired renal insufficiency and increases adverse events in older patients undergoing angiography and percutaneous coronary intervention.
Tan Van Nguyen, Nhi Tuyet Quang, Weber Liu, Ngo Thi Kim Trinh, Tu Ngoc Nguyen   +4 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Contrast-induced nephropathy after computed tomography

Brazilian Journal of Nephrology, 2015
Introduction: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase.
Luciano da Silva Selistre, Vandréa Carla de Souza, Laurence Dubourg, Mário Bernardes Wagner, João Rubião Hoefel Filho, David Saitovitch   +5 more
doaj   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

British Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus, Pauline Schiro, Jean‐Luc Faillie, Romane Freppel, Johana Béné, Claire de Canecaude, François Montastruc   +6 more
wiley   +1 more source

Contrast induced nephropathy by interventionist cardiology

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2017
Introduction: The damage of kidney function due to the use of contrast agents (nephropathy induced by contrast agents) has been increased in the last years because of a higher number of interventionist procedures has been performance in patients with ...
Dra. Xiomara Castelo Villalón, Dra. Yudmila Reina Borges Moreno, Dra. Grisel Guevara Mirabal, Dra. Anneris Martínez Carrillo, Dra. Sheila Hechavarría Pouymiro, Lic. Jilka Lietys García Romero   +5 more
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