Results 61 to 70 of about 59,047 (268)
Contrast agents and renal cell apoptosis
Contrast media (CM) induce a direct toxic effect on renal tubular cells. This toxic effect may have a role in the pathophysiology of contrast nephropathy.
Romano, Giulia
core
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted therapies remain ...
Shao‐qi Wu +11 more
wiley +1 more source
This study aimed to explore the correlation of sodium ferulate and the renal protective effect on computed tomography pulmonary angiography in patients suffering from pulmonary hypertension.
Ying Zhao +9 more
doaj +1 more source
Current therapeutic management of diabetic nephropathy
Roughly 40% of all patients with insulin-dependent diabetes mellitus (IDDM) develop diabetic nephropathy with proteinuria, hypertension and a decrease in glomerular filtration rate 10 to 20 years after the onset of the disease, and 5 years later most ...
Kohler, S. M., Krämer, Bernhard K.
core +1 more source
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza +2 more
wiley +1 more source
Contrast induced nephropathy by interventionist cardiology
Introduction: The damage of kidney function due to the use of contrast agents (nephropathy induced by contrast agents) has been increased in the last years because of a higher number of interventionist procedures has been performance in patients with ...
Dra. Xiomara Castelo Villalón +5 more
doaj
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan +5 more
wiley +1 more source
Contrast-induced nephropathy in invasive cardiology
Contrast-induced nephropathy (CIN) is an acute renal injury due to the renal toxicity of iodinated contrast media. It is classically defined as a relative (≥25%) or absolute (≥0.5 mg/dl; 44 μmol/l) increase in serum creatinine from baseline value ...
Tilman N.U. Perrin +2 more
doaj +1 more source
Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Segerer, Stephan +7 more
core +1 more source

