Results 121 to 130 of about 899,795 (311)
Preclinical Applications of Targeted Protein-Based Contrast Agents for Molecular MRI Imaging
Magnetic resonance imaging (MRI) is a powerful technique for disease diagnosis, but extending this technology to applications in molecular imaging has been challenging due to lack of safe and effective contrast agents with required sensitivity and ...
Gui, Zongxiang
core +1 more source
OpenNanoMRI is a powerful, non-invasive imaging technique with exceptional soft tissue contrast, requiring contrast agents to enhance sensitivity by shortening longitudinal (T1) and transverse (T2) relaxation times.
Azmi Aulia Rahmani +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Microbubbling and microencapsulation by co-axial electrohydrodynamic atomization
, 2009 Microbubbles coated with polymers or surfactants have been used in medical imaging for several years as ultrasound contrast agent particles and are now being investigated by researchers as drug and gene delivery vehicles and blood substitutes. Current
Farook, U.
core
Hepatobiliary-Specific Contrast Agent in Biliary Leak
Journal of the Belgian Society of Radiology, 2018 Laurent Médart +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Nonionic contrast neurotoxicity after coronary angiography mimicking subarachnoid hemorrhage [PDF]
, 2003 Milz, P. +4 more
core +1 more source
, 2012 Short-axis cine images are acquired during cardiac MRI in order to determine variables of cardiac left ventricular (LV) function such as ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and LV mass.
Crowe, E. A. +15 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source