Results 61 to 70 of about 11,213,834 (373)

Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]

open access: yes, 2018
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming   +12 more
core  

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

open access: yesPopulation Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Assessing Changes in Dielectric Properties Due to Nanomaterials Using a Two-Port Microwave System

open access: yesSensors, 2020
Detecting changes in the dielectric properties of tissues at microwave frequencies can offer simple and cost effective tools for cancer detection. These changes can be enhanced by the use of nanoparticles (NPs) that are characterised by both increased ...
Mohammed Rahman   +4 more
doaj   +1 more source

Image enhancement using an improved adaptive contrast enhancement algorithm in neutron radiography

open access: yesAIP Advances, 2023
As a non-destructive testing technique, neutron radiography has received increasing attention in scientific research. However, the inherent limitations of neutron images, such as insufficient resolution and contrast, have been attributed to the low ...
Wangtao Yu, Peng Xu, Jie Bao, Man Zhou
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Contrast-Enhancing Spatial–Frequency Deconvolution-Aided Interferometric Scattering Microscopy (iSCAT)

open access: yesPhotonics
Interferometric scattering microscopy (iSCAT) is widely used for label-free tracking of nanoparticles and single molecules. However, its ability to identify small molecules is limited by low imaging contrast blurred with noise.
Xiang Zhang, Hao He
doaj   +1 more source

Memory Performance for Everyday Motivational and Neutral Objects Is Dissociable from Attention [PDF]

open access: yes, 2017
Episodic memory is typically better for items coupled with monetary reward or punishment during encoding. It is yet unclear whether memory is also enhanced for everyday objects with appetitive or aversive values learned through a lifetime of experience ...
Schomaker, Judith, Wittmann, Bianca C.
core   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Non-topographical contrast enhancement in the olfactory bulb

open access: yesBMC Neuroscience, 2006
Background Contrast enhancement within primary stimulus representations is a common feature of sensory systems that regulates the discrimination of similar stimuli.
Sethupathy Praveen, Cleland Thomas A
doaj   +1 more source

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