Results 81 to 90 of about 1,614,820 (292)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Joint Noise Reduction for Contrast Enhancement in Stokes Polarimetric Imaging

open access: yesIEEE Photonics Journal, 2019
Contrast optimization is a key issue in polarimetric imaging for the purpose of target detection. In practice, the noise could induce the intensity fluctuation of the image and thus lead to the decrease of the image contrast.
Hui Wang   +9 more
doaj   +1 more source

Exact Histogram Specification Optimized for Structural Similarity

open access: yes, 2008
An exact histogram specification (EHS) method modifies its input image to have a specified histogram. Applications of EHS include image (contrast) enhancement (e.g., by histogram equalization) and histogram watermarking.
Alireza Nasiri Avanaki   +20 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Dynamic contrast enhancement and flexible odor codes

open access: yesNature Communications, 2018
Sensory stimuli are encountered in multiple ways necessitating a flexible and adaptive neural population code for identification. Here, the authors show that the dynamics of odor coding in the locust antennal lobe varies with stimulus context so as to ...
Srinath Nizampatnam   +3 more
doaj   +1 more source

Quest for consistent modelling of statistical decay of the compound nucleus

open access: yes, 2017
A statistical model description of heavy ion induced fusion-fission reactions is presented where shell effects, collective enhancement of level density, tilting away effect of compound nuclear spin and dissipation are included.
Banerjee, Tathagata   +2 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Contrast Limited Adaptive Local Histogram Equalization Method for Poor Contrast Image Enhancement

open access: yesIEEE Access
Contrast limited adaptive histogram equalization (CLAHE) is a widely utilised method for image enhancement due to its speed and simplicity. However, this method faces two major limitations, namely, the requirement of manual parameter setting (i.e.
Ibrahim Majid Mohammed   +1 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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