Results 101 to 110 of about 3,372,624 (300)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Fast contrast enhancement by adaptive pixel value stretching
International Journal of Distributed Sensor Networks, 2018 In this article, we propose a fast and effective method for digital image contrast enhancement. The gray-level dynamic range of contrast-distorted images is extended maximally via adaptive pixel value stretching.
Gang Cao +3 more
doaj +1 more source
A deep learning approach for virtual contrast enhancement in Contrast Enhanced Spectral Mammography
Computerized Medical Imaging and GraphicsContrast Enhanced Spectral Mammography (CESM) is a dual-energy mammographic imaging technique that first needs intravenously administration of an iodinated contrast medium; then, it collects both a low-energy image, comparable to standard mammography, and a high-energy image.
Aurora Rofena +6 more
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Diffeomorphic Registration of Images with Variable Contrast Enhancement
International Journal of Biomedical Imaging, 2011 Nonrigid image registration is widely used to estimate tissue deformations in highly deformable anatomies. Among the existing methods, nonparametric registration algorithms such as optical flow, or Demons, usually have the advantage of being fast and ...
Guillaume Janssens +4 more
doaj +1 more source
Interactive Evolutionary Algorithms for Image Enhancement and Creation [PDF]
, 2014 Image enhancement and creation, particularly for aesthetic purposes, are tasks for which the use of interactive evolutionary algorithms would seem to be well suited.
Mist, Joseph James
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Manuscripts fidelity in the digital libraries era: the contrast enhancement evaluation conundrum [PDF]
Digitization of ancient manuscripts spurs inter-disciplinary research but the quality may be limited due to manuscript preservation state or scan hardware limitations.
Franchi M. +3 more
core
PURPOSE: To determine whether qualitative and quantitative enhancement parameters obtained from contrast-enhanced mammography (CEM) can be used in predicting malignancy.
Kul, Sibel +5 more
core +1 more source