Results 141 to 150 of about 3,572 (221)

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5476-5491, July 2026.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin   +5 more
wiley   +1 more source

Contrast Induced Nephropathy: Protecting Kidneys, Protecting Lives

open access: yes, 2016
Radiographic imaging procedures using iodinated contrast media are an essential part of the clinical management of many patient conditions, yet these procedures are not without complications.
Yvonne Gallegos
core  

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

open access: yesInternational Endodontic Journal, Volume 59, Issue 7, Page 1402-1415, July 2026.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl   +10 more
wiley   +1 more source

Global kidney health: Are we failing the silent pandemic?

open access: yesJournal of Internal Medicine, Volume 300, Issue 1, Page 26-38, July 2026.
Abstract Chronic kidney disease (CKD), although not infectious, has a sharply rising global incidence, alarming rates of death and disability, and the potential to disrupt health systems and economies. Thus, it demands the urgency and global attention of past pandemics.
Taewon Yi   +2 more
wiley   +1 more source

Efficacy of atorvastatin on the prevention of contrast-induced acute kidney injury: a meta-analysis

open access: yes, 2018
Ling-Yun Liu,1 Yang Liu,2 Mei-Yan Wu,2 Yan-Yan Sun,3 Fu-Zhe Ma2 1Department of Andrology, 2Department of Nephrology, the First Hospital of Jilin University, 3Department of Nephrology, the Fourth Hospital of Jilin University, Changchun, China Background:
Liu Y, Wu M, Liu L, Sun Y, Ma F
core  

Contrast‐enhanced CT—Nephrotoxic or not? A critical review of propensity‐score‐adjusted studies

open access: yesJournal of Internal Medicine, Volume 300, Issue 1, Page 5-25, July 2026.
Abstract Retrospective, propensity‐score‐adjusted (PSA) studies have indicated to practitioners in the field that contrast‐induced acute kidney injury (AKI) after contrast‐enhanced CT (CECT) is of minor importance or even non‐existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant ...
Ulf Nyman   +6 more
wiley   +1 more source

Risk of contrast induced nephropathy in HIV patients receiving radiographic contrast at three Aga Khan Hospitals

open access: yes, 2009
Aim: To study the influence of HIV infection on the development of contrast induced nephropathy in patients receiving radio contrast material Design: Prospective cohort study Patients and setting:One hundred and twenty five (125) HIV positive patients ...
Mwanzi, Sitna A.
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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