Results 151 to 160 of about 3,572 (221)
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
These findings indicate that urinary exosomal miR‐217 promotes podocyte ferroptosis and DKD progression via suppression of the SIRT1/Nrf2 pathway, suggesting a potential therapeutic target for DKD. Abstract Urinary exosomal microRNAs (miRNAs) mediate intercellular communication in diabetic kidney disease (DKD), a leading contributor to end‐stage renal ...
Xin Du +7 more
wiley +1 more source
N‐acetyltransferase 10 (NAT10) catalyses N4‐acetylcytidine (ac4C) modification of PML pre‐mRNA, shifting splicing from the senescence‐promoting PML‐FL to the senescence‐inhibiting PML‐S isoform via SRSF1. This rejuvenates adipose‐derived stem cells (ADSCs) by reducing senescence markers and senescence‐associated secretory phenotype (SASP), thereby ...
Wuhan Wei +9 more
wiley +1 more source
Streptozotocin induced hyperglycemia in the axolotl
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source
Proceedings of the Contrast-Induced Nephropathy Consensus Panel 17 September 2005, Paris, France
Contrast Induced Nephropathy Consensus Panel 2005 Paris +1 more
core +1 more source
Lesson of the week - Acute renal failure induced by contrast medium: steps towards prevention
Woothipoom, W., Haque, K., Mathew, R.
core
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy +7 more
wiley +1 more source
UPLC‐MS/MS analysis of hawthorn flavonoids combined with network pharmacology, molecular docking, and molecular dynamics studies predicted vitexin as a key compound acting on the PPARγ/ABCG2 pathway. In a hyperuricemic mouse model, vitexin effectively lowered serum uric acid by enhancing renal and intestinal urate excretion, inhibiting urate production,
Shu‐Yu Wu +11 more
wiley +1 more source
This study elucidates the multi‐targeted mechanisms of Virgin Coconut Oil (CO) as a dietary intervention for ameliorating Diabetic Kidney Disease (DKD). High‐purity medium‐chain fatty acids (MCFAs, primarily octanoic acid [C8:0] and decanoic acid [C10:0]) in CO significantly remodel the gut microbiota by enriching short‐chain fatty acid (SCFA ...
Keke Shao +13 more
wiley +1 more source
Prevention of contrast induced nephropathy; a cardiology point of view [PDF]
Hashemi Mohammad +2 more
doaj

