Results 61 to 70 of about 3,572 (221)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Renal protective effect of sodium ferulate on pulmonary hypertension patients undergoing computed tomography pulmonary angiography

Pulmonary Circulation, 2020
This study aimed to explore the correlation of sodium ferulate and the renal protective effect on computed tomography pulmonary angiography in patients suffering from pulmonary hypertension.
Ying Zhao, Haiyan Wang, Jiayu Zhao, Xun Wang, Yanbo Wang, Wei Li, Tingting Song, Guozhen Hao, Xianghua Fu, Xinshun Gu   +9 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Contrast induced nephropathy by interventionist cardiology

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2017
Introduction: The damage of kidney function due to the use of contrast agents (nephropathy induced by contrast agents) has been increased in the last years because of a higher number of interventionist procedures has been performance in patients with ...
Dra. Xiomara Castelo Villalón, Dra. Yudmila Reina Borges Moreno, Dra. Grisel Guevara Mirabal, Dra. Anneris Martínez Carrillo, Dra. Sheila Hechavarría Pouymiro, Lic. Jilka Lietys García Romero   +5 more
doaj  

Targeting Renal IGFBP7 With Tetrahedral Framework Nucleic Acid‐Delivered siRNA Alleviates Acute Kidney Injury

iNew Medicine, EarlyView.
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted therapies remain ...
Shao‐qi Wu, Ying‐ying Gao, Meng‐yi Jia, Yu‐Hao Liu, Qian Zhou, Dong Liu, Yu Ren, Yu‐jie Liu, Feng‐he Li, Ya‐ru Yang, Jie Wang, Jia‐gen Wen   +11 more
wiley   +1 more source

DEVELOPMENT AND EVALUATION OF A NURSE PRACTITIONER-DIRECTED CONTRAST-INDUCED NEPHROPATHY AVOIDANCE INITIATIVE IN A COMMUNITY MEDICAL CENTER

, 2022
Contrast-induced nephropathy (CIN) is one of the leading causes of hospital-acquired kidney injury. CIN is associated with significantly higher morbidity and mortality risk, increased length of stay, long-term disability, and financial burden exceeding ...
Frend, Mindi Larae.
core   +1 more source

Contrast-induced nephropathy in invasive cardiology

Swiss Medical Weekly, 2012
Contrast-induced nephropathy (CIN) is an acute renal injury due to the renal toxicity of iodinated contrast media. It is classically defined as a relative (≥25%) or absolute (≥0.5 mg/dl; 44 μmol/l) increase in serum creatinine from baseline value ...
Tilman N.U. Perrin, Eric Descombes, Stephane Cook   +2 more
doaj   +1 more source

Charlson Comorbidity Index predicts contrast-induced nephropathy following transcatheter aortic valve replacement

Introduction Transcatheter aortic valve replacement (TAVR) is increasingly used for the management of patients with severe aortic stenosis at high risk for surgical valve replacement.
İrem B. Bulburu, Nilay Solak, Kenan Yalta, Alparslan Kurtul, Murat Gök, Emirhan Çakır   +5 more
core   +1 more source

Bench-to-bedside review: preventive measures for contrast-induced nephropathy in critically ill patients [PDF]

, 2005
An increasing number of diagnostic imaging procedures requires the use of intravenous radiographic contrast agents, which has led to a parallel increase in the incidence of contrast-induced nephropathy.
Tonino, Sanne, Smit, Watske, van den Berk, Guido, Schultz, Marcus J., van den Berk, G., de Fijter, Carola, Tonino, S., Smit, W., Schultz, M.J., de Fijter, C.   +9 more
core   +1 more source