Results 41 to 50 of about 1,175,265 (311)

The Impact of Radiation Dose on CT‐Based Body Composition Analysis: A Large‐Animal Study

Journal of Cachexia, Sarcopenia and Muscle
Background CT‐based body composition analysis (BCA) enables the extraction of biomarkers from routine CT data. The influence of body composition on the prognosis of different patient groups has been highlighted in recent years.
Luca Salhöfer, Gregor Jost, Mathias Meetschen, Daniel vanLandeghem, Michael Forsting, Denise Bos, Christian Bojahr, Rene Hosch, Felix Nensa, Hubertus Pietsch, Johannes Haubold   +10 more
doaj   +1 more source

Ultrasound contrast agent delivered per os first diagnoses pharyngoesophageal tumour

Journal of the Belgian Society of Radiology, 2013
Oral administration of ultrasound contrast agents has been described very little so far in medical literature. These agents are mainly administered intravenously and, less commonly, intracavitarily.
E Antypa, DD Cokkinos, I Kalogeropoulos, D Tomais, PN Piperopoulos   +4 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

The molecular mechanism of contrast-induced nephropathy (CIN) and its link to in vitro studies on iodinated contrast media (CM)

BioMedicine, 2018
Iodinated contrast media (iodinated CM) have increased ability to absorb x-rays and to visualize structures that normally are impossible to observe in a radiological examination.
Yang Jai-Sing, Peng Yan-Ru, Tsai Shih-Chang, Tyan Yeu-Sheng, Lu Chi-Cheng, Chiu Hong-Yi, Chiu Yu-Jen, Kuo Sheng-Chu, Tsai Yuh-Feng, Lin Ping-Chin, Tsai Fuu-Jen   +10 more
doaj   +1 more source

The Incidence and Associated Risk Factors of Contrast-Induced Nephropathy after Contrast-Enhanced Computed Tomography in the Emergency Setting: A Systematic Review

Life, 2022
Iodinated contrast media (ICM) during contrast-enhanced computed tomography (CECT) in the emergency department (ED) is essential to diagnose acute conditions, despite risks of contrast-induced nephropathy (CIN) development and its associated ...
Mei-Yi Ong, Justin Jie-Hui Koh, Suchart Kothan, Christopher Lai   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Assessment of estimated GFR and clinical predictors of contrast induced nephropathy among diabetic patients undergoing cardiac catheterization

The Egyptian Heart Journal, 2015
Introduction: Contrast-induced nephropathy is a leading cause of morbidity and mortality in high-risk patients. Aim: To study different risk predictors of contrast induced nephropathy, among diabetic patients with normal serum creatinine undergoing ...
Tarek Zaki, Ayman Samir, Tarek Mohammed Rashid, Haitham Galal, Wesam Samir   +4 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source